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RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells.
Otto C, Kastner C, Schmidt S, Uttinger K, Baluapuri A, Denk S, Rosenfeldt MT, Rosenwald A, Roehrig F, Ade CP, Schuelein-Voelk C, Diefenbacher ME, Germer CT, Wolf E, Eilers M, Wiegering A. Otto C, et al. Among authors: germer ct. Mol Oncol. 2022 Aug;16(15):2788-2809. doi: 10.1002/1878-0261.13265. Epub 2022 Jul 1. Mol Oncol. 2022. PMID: 35673898 Free PMC article.
Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress.
Klingelhoeffer C, Kämmerer U, Koospal M, Mühling B, Schneider M, Kapp M, Kübler A, Germer CT, Otto C. Klingelhoeffer C, et al. Among authors: germer ct. BMC Complement Altern Med. 2012 May 2;12:61. doi: 10.1186/1472-6882-12-61. BMC Complement Altern Med. 2012. PMID: 22551313 Free PMC article.
565 results