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Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM.
NPJ Precis Oncol. 2022 Dec 27;6(1):94. doi: 10.1038/s41698-022-00335-y.
NPJ Precis Oncol. 2022.
PMID: 36575299
Free PMC article.
The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.
Sigaud R, Rösch L, Gatzweiler C, Benzel J, von Soosten L, Peterziel H, Selt F, Najafi S, Ayhan S, Gerloff XF, Hofmann N, Büdenbender I, Schmitt L, Foerster KI, Burhenne J, Haefeli WE, Korshunov A, Sahm F, van Tilburg CM, Jones DTW, Pfister SM, Knoerzer D, Kreider BL, Sauter M, Pajtler KW, Zuckermann M, Oehme I, Witt O, Milde T.
Sigaud R, et al. Among authors: gerloff xf.
Neuro Oncol. 2023 Mar 14;25(3):566-579. doi: 10.1093/neuonc/noac183.
Neuro Oncol. 2023.
PMID: 35882450
Free PMC article.
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Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models.
Gatzweiler C, Ridinger J, Herter S, Gerloff XF, ElHarouni D, Berker Y, Imle R, Schmitt L, Kreth S, Stainczyk S, Ayhan S, Najafi S, Krunic D, Frese K, Meder B, Reuss D, Fiesel P, Schramm K, Blattner-Johnson M, Jones DTW, Banito A, Westermann F, Oppermann S, Milde T, Peterziel H, Witt O, Oehme I.
Gatzweiler C, et al. Among authors: gerloff xf.
Cancers (Basel). 2022 Feb 8;14(3):849. doi: 10.3390/cancers14030849.
Cancers (Basel). 2022.
PMID: 35159116
Free PMC article.
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Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma.
Müller M, Rösch L, Najafi S, Gatzweiler C, Ridinger J, Gerloff XF, Jones DTW, Baßler J, Kreth S, Stainczyk S, Frese K, Meder B, Westermann F, Milde T, Peterziel H, Witt O, Oehme I.
Müller M, et al. Among authors: gerloff xf.
Cancers (Basel). 2021 Sep 5;13(17):4476. doi: 10.3390/cancers13174476.
Cancers (Basel). 2021.
PMID: 34503286
Free PMC article.
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Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma.
Körholz K, Ridinger J, Krunic D, Najafi S, Gerloff XF, Frese K, Meder B, Peterziel H, Vega-Rubin-de-Celis S, Witt O, Oehme I.
Körholz K, et al. Among authors: gerloff xf.
Cells. 2021 Apr 24;10(5):1001. doi: 10.3390/cells10051001.
Cells. 2021.
PMID: 33923163
Free PMC article.
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