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α-Synuclein aggregation nucleates through liquid-liquid phase separation.
Ray S, Singh N, Kumar R, Patel K, Pandey S, Datta D, Mahato J, Panigrahi R, Navalkar A, Mehra S, Gadhe L, Chatterjee D, Sawner AS, Maiti S, Bhatia S, Gerez JA, Chowdhury A, Kumar A, Padinhateeri R, Riek R, Krishnamoorthy G, Maji SK. Ray S, et al. Among authors: gerez ja. Nat Chem. 2020 Aug;12(8):705-716. doi: 10.1038/s41557-020-0465-9. Epub 2020 Jun 8. Nat Chem. 2020. PMID: 32514159
Regulation of α-synuclein by chaperones in mammalian cells.
Burmann BM, Gerez JA, Matečko-Burmann I, Campioni S, Kumari P, Ghosh D, Mazur A, Aspholm EE, Šulskis D, Wawrzyniuk M, Bock T, Schmidt A, Rüdiger SGD, Riek R, Hiller S. Burmann BM, et al. Among authors: gerez ja. Nature. 2020 Jan;577(7788):127-132. doi: 10.1038/s41586-019-1808-9. Epub 2019 Dec 4. Nature. 2020. PMID: 31802003 Free PMC article.
Preparation and Characterization of Stable α-Synuclein Lipoprotein Particles.
Eichmann C, Campioni S, Kowal J, Maslennikov I, Gerez J, Liu X, Verasdonck J, Nespovitaya N, Choe S, Meier BH, Picotti P, Rizo J, Stahlberg H, Riek R. Eichmann C, et al. J Biol Chem. 2016 Apr 15;291(16):8516-27. doi: 10.1074/jbc.M115.707968. Epub 2016 Feb 4. J Biol Chem. 2016. PMID: 26846854 Free PMC article.
More than a Rumor Spreads in Parkinson's Disease.
Prymaczok NC, Riek R, Gerez J. Prymaczok NC, et al. Front Hum Neurosci. 2016 Dec 2;10:608. doi: 10.3389/fnhum.2016.00608. eCollection 2016. Front Hum Neurosci. 2016. PMID: 27994545 Free PMC article. Review.
Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity.
Soste M, Charmpi K, Lampert F, Gerez JA, van Oostrum M, Malinovska L, Boersema PJ, Prymaczok NC, Riek R, Peter M, Vanni S, Beyer A, Picotti P. Soste M, et al. Among authors: gerez ja. Cell Syst. 2019 Sep 25;9(3):309-320.e8. doi: 10.1016/j.cels.2019.07.010. Epub 2019 Sep 11. Cell Syst. 2019. PMID: 31521608 Free PMC article.
35 results