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SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney.
Francis ME, Goncin U, Kroeker A, Swan C, Ralph R, Lu Y, Etzioni AL, Falzarano D, Gerdts V, Machtaler S, Kindrachuk J, Kelvin AA. Francis ME, et al. Among authors: gerdts v. PLoS Pathog. 2021 Jul 15;17(7):e1009705. doi: 10.1371/journal.ppat.1009705. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34265022 Free PMC article.
Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis.
Garlapati S, Eng NF, Kiros TG, Kindrachuk J, Mutwiri GK, Hancock RE, Halperin SA, Potter AA, Babiuk LA, Gerdts V. Garlapati S, et al. Among authors: gerdts v. Vaccine. 2011 Sep 2;29(38):6540-8. doi: 10.1016/j.vaccine.2011.07.009. Epub 2011 Jul 21. Vaccine. 2011. PMID: 21771625 Free article.
Subclinical in utero Zika virus infection is associated with interferon alpha sequelae and sex-specific molecular brain pathology in asymptomatic porcine offspring.
Trus I, Udenze D, Cox B, Berube N, Nordquist RE, van der Staay FJ, Huang Y, Kobinger G, Safronetz D, Gerdts V, Karniychuk U. Trus I, et al. Among authors: gerdts v. PLoS Pathog. 2019 Nov 14;15(11):e1008038. doi: 10.1371/journal.ppat.1008038. eCollection 2019 Nov. PLoS Pathog. 2019. PMID: 31725819 Free PMC article.
Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets.
Francis ME, Richardson B, McNeil M, Rioux M, Foley MK, Ge A, Pechous RD, Kindrachuk J, Cameron CM, Richardson C, Lew J, Cameron MJ, Gerdts V, Falzarano D, Kelvin AA. Francis ME, et al. Among authors: gerdts v. bioRxiv [Preprint]. 2021 Jan 12:2021.01.12.426381. doi: 10.1101/2021.01.12.426381. bioRxiv. 2021. PMID: 33469587 Free PMC article. Updated. Preprint.
Centenarians and extremely old people living with frailty can elicit durable SARS-CoV-2 spike specific IgG antibodies with virus neutralization functions following virus infection as determined by serological study.
Foley MK, Searle SD, Toloue A, Booth R, Falkenham A, Falzarano D, Rubino S, Francis ME, McNeil M, Richardson C, LeBlanc J, Oldford S, Gerdts V, Andrew MK, McNeil SA, Clarke B, Rockwood K, Kelvin DJ, Kelvin AA. Foley MK, et al. Among authors: gerdts v. EClinicalMedicine. 2021 Jul;37:100975. doi: 10.1016/j.eclinm.2021.100975. Epub 2021 Jun 27. EClinicalMedicine. 2021. PMID: 34222846 Free PMC article.
Sex and age bias viral burden and interferon responses during SARS-CoV-2 infection in ferrets.
Francis ME, Richardson B, Goncin U, McNeil M, Rioux M, Foley MK, Ge A, Pechous RD, Kindrachuk J, Cameron CM, Richardson C, Lew J, Machtaler S, Cameron MJ, Gerdts V, Falzarano D, Kelvin AA. Francis ME, et al. Among authors: gerdts v. Sci Rep. 2021 Jul 15;11(1):14536. doi: 10.1038/s41598-021-93855-9. Sci Rep. 2021. PMID: 34267262 Free PMC article.
Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants.
Banerjee A, Lew J, Kroeker A, Baid K, Aftanas P, Nirmalarajah K, Maguire F, Kozak R, McDonald R, Lang A, Gerdts V, Straus SE, Gilbert L, Li AX, Mozafarihashjin M, Walmsley S, Gingras AC, Wrana JL, Mazzulli T, Colwill K, McGeer AJ, Mubareka S, Falzarano D. Banerjee A, et al. Among authors: gerdts v. Med. 2022 Jun 10;3(6):422-432.e3. doi: 10.1016/j.medj.2022.04.002. Epub 2022 Apr 14. Med. 2022. PMID: 35437520 Free PMC article.
151 results