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miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4.
De Logu F, Maglie R, Titiz M, Poli G, Landini L, Marini M, Souza Monteiro de Araujo D, De Siena G, Montini M, Cabrini DA, Otuki MF, Pawloski PL, Antiga E, Tuccinardi T, Calixto JB, Geppetti P, Nassini R, André E. De Logu F, et al. Among authors: geppetti p. J Invest Dermatol. 2023 Jan;143(1):142-153.e10. doi: 10.1016/j.jid.2022.08.034. Epub 2022 Aug 30. J Invest Dermatol. 2023. PMID: 36049541 Free article.
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P. Trevisani M, et al. Among authors: geppetti p. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13519-24. doi: 10.1073/pnas.0705923104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684094 Free PMC article.
The concept of neurogenic inflammation.
Geppetti P, Nassini R, Materazzi S, Benemei S. Geppetti P, et al. BJU Int. 2008 Mar;101 Suppl 3:2-6. doi: 10.1111/j.1464-410X.2008.07493.x. BJU Int. 2008. PMID: 18307678 Review.
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R. Andrè E, et al. Among authors: geppetti p. J Clin Invest. 2008 Jul;118(7):2574-82. doi: 10.1172/JCI34886. J Clin Invest. 2008. PMID: 18568077 Free PMC article.
Ethanol potentiates the TRPV1-mediated cough in the guinea pig.
Gatti R, Andre E, Barbara C, Dinh TQ, Fontana G, Fischer A, Geppetti P, Trevisani M. Gatti R, et al. Among authors: geppetti p. Pulm Pharmacol Ther. 2009 Feb;22(1):33-6. doi: 10.1016/j.pupt.2008.11.001. Epub 2008 Nov 14. Pulm Pharmacol Ther. 2009. PMID: 19049892
414 results