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The Key Role of GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates.
Antioxidants (Basel). 2023 Nov 1;12(11):1953. doi: 10.3390/antiox12111953.
Antioxidants (Basel). 2023.
PMID: 38001806
Free PMC article.
Review.
Recruiting In Vitro Transcribed mRNA against Cancer Immunotherapy: A Contemporary Appraisal of the Current Landscape.
Miliotou AN, Georgiou-Siafis SK, Ntenti C, Pappas IS, Papadopoulou LC.
Miliotou AN, et al. Among authors: georgiou siafis sk.
Curr Issues Mol Biol. 2023 Nov 16;45(11):9181-9214. doi: 10.3390/cimb45110576.
Curr Issues Mol Biol. 2023.
PMID: 37998753
Free PMC article.
Review.
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An Innovative PTD-IVT-mRNA Delivery Platform for CAR Immunotherapy of ErbB(+) Solid Tumor Neoplastic Cells.
Georgiou-Siafis SK, Miliotou AN, Ntenti C, Pappas IS, Papadopoulou LC.
Georgiou-Siafis SK, et al.
Biomedicines. 2022 Nov 10;10(11):2885. doi: 10.3390/biomedicines10112885.
Biomedicines. 2022.
PMID: 36359405
Free PMC article.
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Glutathione-Hemin/Hematin Adduct Formation to Disintegrate Cytotoxic Oxidant Hemin/Hematin in Human K562 Cells and Red Blood Cells' Hemolysates: Impact of Glutathione on the Hemolytic Disorders and Homeostasis.
Georgiou-Siafis SK, Samiotaki MK, Demopoulos VJ, Panayotou G, Tsiftsoglou AS.
Georgiou-Siafis SK, et al.
Antioxidants (Basel). 2022 Sep 30;11(10):1959. doi: 10.3390/antiox11101959.
Antioxidants (Basel). 2022.
PMID: 36290682
Free PMC article.
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Hemin accumulation and identification of a heme-binding protein clan in K562 cells by proteomic and computational analysis.
Tsolaki VC, Georgiou-Siafis SK, Tsamadou AI, Tsiftsoglou SA, Samiotaki M, Panayotou G, Tsiftsoglou AS.
Tsolaki VC, et al. Among authors: georgiou siafis sk.
J Cell Physiol. 2022 Feb;237(2):1315-1340. doi: 10.1002/jcp.30595. Epub 2021 Oct 7.
J Cell Physiol. 2022.
PMID: 34617268
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Formation of novel N-acetylcysteine-hemin adducts abrogates hemin-induced cytotoxicity and suppresses the NRF2-driven stress response in human pro-erythroid K562 cells.
Georgiou-Siafis SK, Samiotaki MK, Demopoulos VJ, Panayotou G, Tsiftsoglou AS.
Georgiou-Siafis SK, et al.
Eur J Pharmacol. 2020 Aug 5;880:173077. doi: 10.1016/j.ejphar.2020.173077. Epub 2020 Mar 25.
Eur J Pharmacol. 2020.
PMID: 32222495
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Activation of KEAP1/NRF2 stress signaling involved in the molecular basis of hemin-induced cytotoxicity in human pro-erythroid K562 cells.
Georgiou-Siafis SK, Tsiftsoglou AS.
Georgiou-Siafis SK, et al.
Biochem Pharmacol. 2020 May;175:113900. doi: 10.1016/j.bcp.2020.113900. Epub 2020 Mar 7.
Biochem Pharmacol. 2020.
PMID: 32156661
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