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Page 1
A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Acosta JC, Banito A, Wuestefeld T, Georgilis A, Janich P, Morton JP, Athineos D, Kang TW, Lasitschka F, Andrulis M, Pascual G, Morris KJ, Khan S, Jin H, Dharmalingam G, Snijders AP, Carroll T, Capper D, Pritchard C, Inman GJ, Longerich T, Sansom OJ, Benitah SA, Zender L, Gil J. Acosta JC, et al. Among authors: georgilis a. Nat Cell Biol. 2013 Aug;15(8):978-90. doi: 10.1038/ncb2784. Epub 2013 Jun 16. Nat Cell Biol. 2013. PMID: 23770676 Free PMC article.
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Among authors: georgilis a. Nat Cell Biol. 2015 Sep;17(9):1205-17. doi: 10.1038/ncb3225. Epub 2015 Aug 17. Nat Cell Biol. 2015. PMID: 26280535 Free PMC article.
Erratum: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Among authors: georgilis a. Nat Cell Biol. 2015 Oct;17(10):1370. doi: 10.1038/ncb3243. Nat Cell Biol. 2015. PMID: 26419804 No abstract available.
Controlling secretion to limit chemoresistance.
Georgilis A, Gil J. Georgilis A, et al. Genes Dev. 2016 Aug 15;30(16):1791-2. doi: 10.1101/gad.288571.116. Genes Dev. 2016. PMID: 27601527 Free PMC article.
PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
Georgilis A, Klotz S, Hanley CJ, Herranz N, Weirich B, Morancho B, Leote AC, D'Artista L, Gallage S, Seehawer M, Carroll T, Dharmalingam G, Wee KB, Mellone M, Pombo J, Heide D, Guccione E, Arribas J, Barbosa-Morais NL, Heikenwalder M, Thomas GJ, Zender L, Gil J. Georgilis A, et al. Cancer Cell. 2018 Jul 9;34(1):85-102.e9. doi: 10.1016/j.ccell.2018.06.007. Cancer Cell. 2018. PMID: 29990503 Free PMC article.
Autophagic degradation of CNS myelin maintains axon integrity.
Ktena N, Kaplanis SI, Kolotuev I, Georgilis A, Kallergi E, Stavroulaki V, Nikoletopoulou V, Savvaki M, Karagogeos D. Ktena N, et al. Among authors: georgilis a. Cell Stress. 2022 Nov 21;6(12):93-107. doi: 10.15698/cst2022.12.274. eCollection 2022 Dec. Cell Stress. 2022. PMID: 36478958 Free PMC article.
Effect of Neonatal Treatment With the NMDA Receptor Antagonist, MK-801, During Different Temporal Windows of Postnatal Period in Adult Prefrontal Cortical and Hippocampal Function.
Plataki ME, Diskos K, Sougklakos C, Velissariou M, Georgilis A, Stavroulaki V, Sidiropoulou K. Plataki ME, et al. Among authors: georgilis a. Front Behav Neurosci. 2021 Jun 11;15:689193. doi: 10.3389/fnbeh.2021.689193. eCollection 2021. Front Behav Neurosci. 2021. PMID: 34177484 Free PMC article.
Novel regulation of PLCζ activity via its XY-linker.
Nomikos M, Elgmati K, Theodoridou M, Georgilis A, Gonzalez-Garcia JR, Nounesis G, Swann K, Lai FA. Nomikos M, et al. Among authors: georgilis a. Biochem J. 2011 Sep 15;438(3):427-32. doi: 10.1042/BJ20110953. Biochem J. 2011. PMID: 21767260 Free PMC article.