George-Hyslop PS - Search Results

1

Anti-amyloid-β-mediated positron emission tomography imaging in Alzheimer's disease mouse brains.

McLean D, Cooke MJ, Wang Y, Green D, Fraser PE, George-Hyslop PS, Shoichet MS. McLean D, et al. PLoS One. 2012;7(12):e51958. doi: 10.1371/journal.pone.0051958. Epub 2012 Dec 21. PLoS One. 2012. PMID: 23284831 Free PMC article.

2

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

De Strooper B, Beullens M, Contreras B, Levesque L, Craessaerts K, Cordell B, Moechars D, Bollen M, Fraser P, George-Hyslop PS, Van Leuven F. De Strooper B, et al. J Biol Chem. 1997 Feb 7;272(6):3590-8. doi: 10.1074/jbc.272.6.3590. J Biol Chem. 1997. PMID: 9013610 Free article.

3

Localisation of presenilin 2 in human and rodent pancreatic islet beta-cells; Met239Val presenilin 2 variant is not associated with diabetes in man.

Jaikaran ET, Marcon G, Levesque L, George-Hyslop PS, Fraser PE, Clark A. Jaikaran ET, et al. J Cell Sci. 1999 Jul;112 ( Pt 13):2137-44. doi: 10.1242/jcs.112.13.2137. J Cell Sci. 1999. PMID: 10362543

4

Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes.

Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser PE, Haass C, George-Hyslop PS. Yu G, et al. J Biol Chem. 2000 Sep 1;275(35):27348-53. doi: 10.1074/jbc.M002982200. J Biol Chem. 2000. PMID: 10856299 Free article.

5

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, Pearson J, Strome R, Zuker N, Loukides J, French J, Turner S, Lozza G, Grilli M, Kunicki S, Morissette C, Paquette J, Gervais F, Bergeron C, Fraser PE, Carlson GA, George-Hyslop PS, Westaway D. Chishti MA, et al. J Biol Chem. 2001 Jun 15;276(24):21562-70. doi: 10.1074/jbc.M100710200. Epub 2001 Mar 15. J Biol Chem. 2001. PMID: 11279122 Free article.

6

Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts.

Vardarajan B, Vergote D, Tissir F, Logue M, Yang J, Daude N, Ando K, Rogaeva E, Lee J, Cheng R, Brion JP, Ghani M, Shi B, Baldwin CT, Kar S, Mayeux R, Fraser P, Goffinet AM, George-Hyslop PS, Farrer LA, Westaway D. Vardarajan B, et al. Mol Neurodegener. 2013 Feb 15;8:10. doi: 10.1186/1750-1326-8-10. Mol Neurodegener. 2013. PMID: 23414597 Free PMC article.

7

Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice.

Kanemoto S, Griffin J, Markham-Coultes K, Aubert I, Tandon A, George-Hyslop PS, Fraser PE. Kanemoto S, et al. Neuroscience. 2014 Mar 7;261(100):52-9. doi: 10.1016/j.neuroscience.2013.12.021. Epub 2013 Dec 20. Neuroscience. 2014. PMID: 24361736 Free PMC article.

8

Alzheimer amyloid peptide aβ42 regulates gene expression of transcription and growth factors.

Barucker C, Sommer A, Beckmann G, Eravci M, Harmeier A, Schipke CG, Brockschnieder D, Dyrks T, Althoff V, Fraser PE, Hazrati LN, George-Hyslop PS, Breitner JC, Peters O, Multhaup G. Barucker C, et al. J Alzheimers Dis. 2015;44(2):613-24. doi: 10.3233/JAD-141902. J Alzheimers Dis. 2015. PMID: 25318543

9

Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons.

Annaert WG, Levesque L, Craessaerts K, Dierinck I, Snellings G, Westaway D, George-Hyslop PS, Cordell B, Fraser P, De Strooper B. Annaert WG, et al. J Cell Biol. 1999 Oct 18;147(2):277-94. doi: 10.1083/jcb.147.2.277. J Cell Biol. 1999. PMID: 10525535 Free PMC article.

10

Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations.

Katayama T, Imaizumi K, Honda A, Yoneda T, Kudo T, Takeda M, Mori K, Rozmahel R, Fraser P, George-Hyslop PS, Tohyama M. Katayama T, et al. J Biol Chem. 2001 Nov 16;276(46):43446-54. doi: 10.1074/jbc.M104096200. Epub 2001 Sep 10. J Biol Chem. 2001. PMID: 11551913 Free article.

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