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VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation.
Grieder TE, Herman MA, Contet C, Tan LA, Vargas-Perez H, Cohen A, Chwalek M, Maal-Bared G, Freiling J, Schlosburg JE, Clarke L, Crawford E, Koebel P, Repunte-Canonigo V, Sanna PP, Tapper AR, Roberto M, Kieffer BL, Sawchenko PE, Koob GF, van der Kooy D, George O. Grieder TE, et al. Among authors: george o. Nat Neurosci. 2014 Dec;17(12):1751-8. doi: 10.1038/nn.3872. Epub 2014 Nov 17. Nat Neurosci. 2014. PMID: 25402857 Free PMC article.
Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals.
Vendruscolo LF, Estey D, Goodell V, Macshane LG, Logrip ML, Schlosburg JE, McGinn MA, Zamora-Martinez ER, Belanoff JK, Hunt HJ, Sanna PP, George O, Koob GF, Edwards S, Mason BJ. Vendruscolo LF, et al. Among authors: george o. J Clin Invest. 2015 Aug 3;125(8):3193-7. doi: 10.1172/JCI79828. Epub 2015 Jun 29. J Clin Invest. 2015. PMID: 26121746 Free PMC article. Clinical Trial.
203 results