Geoghagen NS - Search Results

1

Label-free high-throughput screening via mass spectrometry: a single cystathionine quantitative method for multiple applications.

Holt TG, Choi BK, Geoghagen NS, Jensen KK, Luo Q, LaMarr WA, Makara GM, Malkowitz L, Ozbal CC, Xiong Y, Dufresne C, Luo MJ. Holt TG, et al. Among authors: geoghagen ns. Assay Drug Dev Technol. 2009 Oct;7(5):495-506. doi: 10.1089/adt.2009.0200. Assay Drug Dev Technol. 2009. PMID: 19715455

2

Pharmacological activation and genetic manipulation of cystathionine beta-synthase alter circulating levels of homocysteine and hydrogen sulfide in mice.

Jensen KK, Geoghagen NS, Jin L, Holt TG, Luo Q, Malkowitz L, Ni W, Quan S, Waters MG, Zhang A, Zhou HH, Cheng K, Luo MJ. Jensen KK, et al. Among authors: geoghagen ns. Eur J Pharmacol. 2011 Jan 10;650(1):86-93. doi: 10.1016/j.ejphar.2010.09.080. Epub 2010 Oct 15. Eur J Pharmacol. 2011. PMID: 20955694

3

An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.

Zhang L, McCabe T, Condra JH, Ni YG, Peterson LB, Wang W, Strack AM, Wang F, Pandit S, Hammond H, Wood D, Lewis D, Rosa R, Mendoza V, Cumiskey AM, Johns DG, Hansen BC, Shen X, Geoghagen N, Jensen K, Zhu L, Wietecha K, Wisniewski D, Huang L, Zhao JZ, Ernst R, Hampton R, Haytko P, Ansbro F, Chilewski S, Chin J, Mitnaul LJ, Pellacani A, Sparrow CP, An Z, Strohl W, Hubbard B, Plump AS, Blom D, Sitlani A. Zhang L, et al. Int J Biol Sci. 2012;8(3):310-27. doi: 10.7150/ijbs.3524. Epub 2012 Feb 9. Int J Biol Sci. 2012. PMID: 22355267 Free PMC article.

4

Validation of human ApoB and ApoAI immunoturbidity assays for non-human primate dyslipidemia and atherosclerosis research.

Chen Z, Strack AM, Stefanni AC, Chen Y, Wu W, Pan Y, Urosevic-Price O, Wang L, McLaughlin T, Geoghagen N, Lassman ME, Roddy TP, Wong KK, Hubbard BK, Flattery AM. Chen Z, et al. J Cardiovasc Transl Res. 2011 Jun;4(3):373-83. doi: 10.1007/s12265-011-9264-4. Epub 2011 Mar 11. J Cardiovasc Transl Res. 2011. PMID: 21394531

5

Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters.

Chen Z, Wang SP, Krsmanovic ML, Castro-Perez J, Gagen K, Mendoza V, Rosa R, Shah V, He T, Stout SJ, Geoghagen NS, Lee SH, McLaren DG, Wang L, Roddy TP, Plump AS, Hubbard BK, Sinz CJ, Johns DG. Chen Z, et al. Among authors: geoghagen ns. Metabolism. 2012 Apr;61(4):470-81. doi: 10.1016/j.metabol.2011.08.006. Epub 2011 Oct 14. Metabolism. 2012. PMID: 22001333

6

Comparison of lipoprotein separation and lipid analysis methodologies for human and cynomolgus monkey plasma samples.

Han S, Flattery AM, McLaren D, Raubertas R, Lee SH, Mendoza V, Rosa R, Geoghagen N, Castro-Perez JM, Roddy TP, Forrest G, Johns D, Hubbard BK, Li J. Han S, et al. J Cardiovasc Transl Res. 2012 Feb;5(1):75-83. doi: 10.1007/s12265-011-9340-9. Epub 2011 Dec 23. J Cardiovasc Transl Res. 2012. PMID: 22194019

7

Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia.

Yin W, Carballo-Jane E, McLaren DG, Mendoza VH, Gagen K, Geoghagen NS, McNamara LA, Gorski JN, Eiermann GJ, Petrov A, Wolff M, Tong X, Wilsie LC, Akiyama TE, Chen J, Thankappan A, Xue J, Ping X, Andrews G, Wickham LA, Gai CL, Trinh T, Kulick AA, Donnelly MJ, Voronin GO, Rosa R, Cumiskey AM, Bekkari K, Mitnaul LJ, Puig O, Chen F, Raubertas R, Wong PH, Hansen BC, Koblan KS, Roddy TP, Hubbard BK, Strack AM. Yin W, et al. Among authors: geoghagen ns. J Lipid Res. 2012 Jan;53(1):51-65. doi: 10.1194/jlr.M019927. Epub 2011 Oct 23. J Lipid Res. 2012. PMID: 22021650 Free PMC article.

8

Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide.

Friedhoff LT, Cullen EI, Geoghagen NS, Buxbaum JD. Friedhoff LT, et al. Among authors: geoghagen ns. Int J Neuropsychopharmacol. 2001 Jun;4(2):127-30. doi: 10.1017/S1461145701002310. Int J Neuropsychopharmacol. 2001. PMID: 11466161 Free article. Clinical Trial.

9

Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Abeta peptide.

Buxbaum JD, Geoghagen NS, Friedhoff LT. Buxbaum JD, et al. Among authors: geoghagen ns. J Alzheimers Dis. 2001 Apr;3(2):221-229. doi: 10.3233/jad-2001-3207. J Alzheimers Dis. 2001. PMID: 12214063

10

Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.

Bult CJ, White O, Olsen GJ, Zhou L, Fleischmann RD, Sutton GG, Blake JA, FitzGerald LM, Clayton RA, Gocayne JD, Kerlavage AR, Dougherty BA, Tomb JF, Adams MD, Reich CI, Overbeek R, Kirkness EF, Weinstock KG, Merrick JM, Glodek A, Scott JL, Geoghagen NS, Venter JC. Bult CJ, et al. Among authors: geoghagen ns. Science. 1996 Aug 23;273(5278):1058-73. doi: 10.1126/science.273.5278.1058. Science. 1996. PMID: 8688087

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