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Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Guthmiller JJ, Han J, Utset HA, Li L, Lan LY, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, de la Peña AT, Rosado V, Dugan HL, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB, Wilson PC. Guthmiller JJ, et al. Among authors: gentles l. Nature. 2022 Feb;602(7896):314-320. doi: 10.1038/s41586-021-04356-8. Epub 2021 Dec 23. Nature. 2022. PMID: 34942633 Free PMC article.
SnapShot: Influenza by the Numbers.
Einav T, Gentles LE, Bloom JD. Einav T, et al. Among authors: gentles le. Cell. 2020 Jul 23;182(2):532-532.e1. doi: 10.1016/j.cell.2020.05.004. Cell. 2020. PMID: 32707094 Free article.
Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage.
Simonich CA, Doepker L, Ralph D, Williams JA, Dhar A, Yaffe Z, Gentles L, Small CT, Oliver B, Vigdorovich V, Mangala Prasad V, Nduati R, Sather DN, Lee KK, Matsen Iv FA, Overbaugh J. Simonich CA, et al. Among authors: gentles l. Nat Commun. 2019 May 16;10(1):2190. doi: 10.1038/s41467-019-09481-7. Nat Commun. 2019. PMID: 31097697 Free PMC article.
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