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A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity.
Sblano S, Cerchia C, Laghezza A, Piemontese L, Brunetti L, Leuci R, Gilardi F, Thomas A, Genovese M, Santi A, Tortorella P, Paoli P, Lavecchia A, Loiodice F. Sblano S, et al. Among authors: genovese m. Eur J Med Chem. 2022 May 5;235:114240. doi: 10.1016/j.ejmech.2022.114240. Epub 2022 Mar 16. Eur J Med Chem. 2022. PMID: 35325635
In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications-A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B.
Ottanà R, Paoli P, Cappiello M, Nguyen TN, Adornato I, Del Corso A, Genovese M, Nesi I, Moschini R, Naß A, Wolber G, Maccari R. Ottanà R, et al. Among authors: genovese m. Molecules. 2021 Jan 10;26(2):330. doi: 10.3390/molecules26020330. Molecules. 2021. PMID: 33435264 Free PMC article.
Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge Dysidea avara.
Casertano M, Genovese M, Santi A, Pranzini E, Balestri F, Piazza L, Del Corso A, Avunduk S, Imperatore C, Menna M, Paoli P. Casertano M, et al. Among authors: genovese m. Pharmaceutics. 2023 Feb 4;15(2):528. doi: 10.3390/pharmaceutics15020528. Pharmaceutics. 2023. PMID: 36839851 Free PMC article.
Suitability of a Cellulose-Based Nanomaterial for the Remediation of Heavy Metal Contaminated Freshwaters: A Case-Study Showing the Recovery of Cadmium Induced DNA Integrity Loss, Cell Proliferation Increase, Nuclear Morphology and Chromosomal Alterations on Dreissena polymorpha.
Guidi P, Bernardeschi M, Palumbo M, Genovese M, Scarcelli V, Fiorati A, Riva L, Punta C, Corsi I, Frenzilli G. Guidi P, et al. Among authors: genovese m. Nanomaterials (Basel). 2020 Sep 14;10(9):1837. doi: 10.3390/nano10091837. Nanomaterials (Basel). 2020. PMID: 32938003 Free PMC article.
Suitability of Nanoparticles to Face Benzo(a)pyrene-Induced Genetic and Chromosomal Damage in M. galloprovincialis. An In Vitro Approach.
Bernardeschi M, Guidi P, Palumbo M, Genovese M, Alfè M, Gargiulo V, Lucchesi P, Scarcelli V, Falleni A, Bergami E, Freyria FS, Bonelli B, Corsi I, Frenzilli G. Bernardeschi M, et al. Among authors: genovese m. Nanomaterials (Basel). 2021 May 15;11(5):1309. doi: 10.3390/nano11051309. Nanomaterials (Basel). 2021. PMID: 34063431 Free PMC article.
504 results