Geng HJ - Search Results

1

Determination of the Pharmacokinetics and Tissue Distribution of Methyl 3,4-Dihydroxybenzoate (MDHB) in Mice Using Liquid Chromatography-Tandem Mass Spectrometry.

Wang JH, Hu SH, Su JY, Pan JP, Mi XN, Geng HJ, Zhang W, Cai L, Su CF, Hong AH, Luo HM. Wang JH, et al. Among authors: geng hj. Eur J Drug Metab Pharmacokinet. 2019 Apr;44(2):237-249. doi: 10.1007/s13318-018-0512-8. Eur J Drug Metab Pharmacokinet. 2019. PMID: 30225640

2

Methyl 3,4-dihydroxybenzoate extends the lifespan of Caenorhabditis elegans, partly via W06A7.4 gene.

Zhang W, Cai L, Geng HJ, Su CF, Yan L, Wang JH, Gao Q, Luo HM. Zhang W, et al. Among authors: geng hj. Exp Gerontol. 2014 Dec;60:108-16. doi: 10.1016/j.exger.2014.10.007. Epub 2014 Oct 16. Exp Gerontol. 2014. PMID: 25456844

3

Neuroprotective Effects of Methyl 3,4-Dihydroxybenzoate against TBHP-Induced Oxidative Damage in SH-SY5Y Cells.

Cai L, Wang LF, Pan JP, Mi XN, Zhang Z, Geng HJ, Wang JH, Hu SH, Zhang W, Gao Q, Wu WT, Luo HM. Cai L, et al. Among authors: geng hj. Molecules. 2016 Aug 22;21(8):1071. doi: 10.3390/molecules21081071. Molecules. 2016. PMID: 27556437 Free PMC article.

4

Methyl 3,4-Dihydroxybenzoate Enhances Resistance to Oxidative Stressors and Lifespan in C. elegans Partially via daf-2/daf-16.

Mi XN, Wang LF, Hu Y, Pan JP, Xin YR, Wang JH, Geng HJ, Hu SH, Gao Q, Luo HM. Mi XN, et al. Among authors: geng hj. Int J Mol Sci. 2018 Jun 5;19(6):1670. doi: 10.3390/ijms19061670. Int J Mol Sci. 2018. PMID: 29874838 Free PMC article.

5

Optimization of Chromeno[2,3- c]pyrrol-9(2 H)-ones as Highly Potent, Selective, and Orally Bioavailable PDE5 Inhibitors: Structure-Activity Relationship, X-ray Crystal Structure, and Pharmacodynamic Effect on Pulmonary Arterial Hypertension.

Wu D, Huang Y, Chen Y, Huang YY, Geng H, Zhang T, Zhang C, Li Z, Guo L, Chen J, Luo HB. Wu D, et al. J Med Chem. 2018 Sep 27;61(18):8468-8473. doi: 10.1021/acs.jmedchem.8b01209. Epub 2018 Sep 7. J Med Chem. 2018. PMID: 30148362

6

Discovery and Optimization of Chromeno[2,3-c]pyrrol-9(2H)-ones as Novel Selective and Orally Bioavailable Phosphodiesterase 5 Inhibitors for the Treatment of Pulmonary Arterial Hypertension.

Wu D, Zhang T, Chen Y, Huang Y, Geng H, Yu Y, Zhang C, Lai Z, Wu Y, Guo X, Chen J, Luo HB. Wu D, et al. J Med Chem. 2017 Aug 10;60(15):6622-6637. doi: 10.1021/acs.jmedchem.7b00523. Epub 2017 Jul 25. J Med Chem. 2017. PMID: 28686445

7

Discovery of Potent, Selective, and Orally Bioavailable Inhibitors against Phosphodiesterase-9, a Novel Target for the Treatment of Vascular Dementia.

Wu Y, Zhou Q, Zhang T, Li Z, Chen YP, Zhang P, Yu YF, Geng H, Tian YJ, Zhang C, Wang Y, Chen JW, Chen Y, Luo HB. Wu Y, et al. J Med Chem. 2019 Apr 25;62(8):4218-4224. doi: 10.1021/acs.jmedchem.8b01041. Epub 2019 Apr 3. J Med Chem. 2019. PMID: 30916555

8

Dimerized sesquiterpenoid [4 + 2] adducts with ferroptosis-promoting activity from Inula britannica Linn.

Guo C, Geng HJ, Wang WJ, Liu YX, Deng L, Tian JM, Gao JM, Tang JJ. Guo C, et al. Among authors: geng hj. Phytochemistry. 2024 Feb;218:113951. doi: 10.1016/j.phytochem.2023.113951. Epub 2023 Dec 12. Phytochemistry. 2024. PMID: 38096962

9

[Impacts of upslope inflow and soil pipe collapse on slope water erosion in the typical Chinese Mollisol region].

Qin QS, Zheng FL, Zhao LY, Mo SH, Wang L, Geng HJ. Qin QS, et al. Among authors: geng hj. Ying Yong Sheng Tai Xue Bao. 2023 Oct;34(10):2703-2712. doi: 10.13287/j.1001-9332.202310.016. Ying Yong Sheng Tai Xue Bao. 2023. PMID: 37897277 Chinese.

10

Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes.

Wang GY, Qin SL, Zheng YN, Geng HJ, Chen L, Yao JH, Deng L. Wang GY, et al. Among authors: geng hj. Anim Nutr. 2023 Jul 22;15:88-98. doi: 10.1016/j.aninu.2023.07.001. eCollection 2023 Dec. Anim Nutr. 2023. PMID: 37841648 Free PMC article.

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