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Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.
Chung PED, Gendoo DMA, Ghanbari-Azarnier R, Liu JC, Jiang Z, Tsui J, Wang DY, Xiao X, Li B, Dubuc A, Shih D, Remke M, Ho B, Garzia L, Ben-David Y, Kang SG, Croul S, Haibe-Kains B, Huang A, Taylor MD, Zacksenhaus E. Chung PED, et al. Among authors: gendoo dma. Nat Commun. 2020 Apr 14;11(1):1825. doi: 10.1038/s41467-020-15585-2. Nat Commun. 2020. PMID: 32286280 Free PMC article.
Integrative Cancer Pharmacogenomics to Infer Large-Scale Drug Taxonomy.
El-Hachem N, Gendoo DMA, Ghoraie LS, Safikhani Z, Smirnov P, Chung C, Deng K, Fang A, Birkwood E, Ho C, Isserlin R, Bader GD, Goldenberg A, Haibe-Kains B. El-Hachem N, et al. Among authors: gendoo dma. Cancer Res. 2017 Jun 1;77(11):3057-3069. doi: 10.1158/0008-5472.CAN-17-0096. Epub 2017 Mar 17. Cancer Res. 2017. PMID: 28314784
CD73 is associated with poor prognosis in high-grade serous ovarian cancer.
Turcotte M, Spring K, Pommey S, Chouinard G, Cousineau I, George J, Chen GM, Gendoo DM, Haibe-Kains B, Karn T, Rahimi K, Le Page C, Provencher D, Mes-Masson AM, Stagg J. Turcotte M, et al. Cancer Res. 2015 Nov 1;75(21):4494-503. doi: 10.1158/0008-5472.CAN-14-3569. Epub 2015 Sep 11. Cancer Res. 2015. PMID: 26363007
Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer.
Gendoo DMA, Denroche RE, Zhang A, Radulovich N, Jang GH, Lemire M, Fischer S, Chadwick D, Lungu IM, Ibrahimov E, Cao PJ, Stein LD, Wilson JM, Bartlett JMS, Tsao MS, Dhani N, Hedley D, Gallinger S, Haibe-Kains B. Gendoo DMA, et al. PLoS Comput Biol. 2019 Jan 10;15(1):e1006596. doi: 10.1371/journal.pcbi.1006596. eCollection 2019 Jan. PLoS Comput Biol. 2019. PMID: 30629588 Free PMC article.
The anti-tumour activity of DNA methylation inhibitor 5-aza-2'-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress.
Gleneadie HJ, Baker AH, Batis N, Bryant J, Jiang Y, Clokie SJH, Mehanna H, Garcia P, Gendoo DMA, Roberts S, Burley M, Molinolo AA, Gutkind JS, Scheven BA, Cooper PR, Parish JL, Khanim FL, Wiench M. Gleneadie HJ, et al. Among authors: gendoo dma. Cancer Lett. 2021 Mar 31;501:172-186. doi: 10.1016/j.canlet.2020.12.029. Epub 2021 Jan 5. Cancer Lett. 2021. PMID: 33359448 Free PMC article.
27 results