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β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.
Beyer C, Schramm A, Akhmetshina A, Dees C, Kireva T, Gelse K, Sonnylal S, de Crombrugghe B, Taketo MM, Distler O, Schett G, Distler JH. Beyer C, et al. Among authors: gelse k. Ann Rheum Dis. 2012 May;71(5):761-7. doi: 10.1136/annrheumdis-2011-200568. Epub 2012 Feb 10. Ann Rheum Dis. 2012. PMID: 22328737 Free PMC article.
Inhibition of sumoylation prevents experimental fibrosis.
Khodzhigorova A, Distler A, Lang V, Dees C, Schneider H, Beyer C, Gelse K, Distler O, Schett G, Distler JH. Khodzhigorova A, et al. Among authors: gelse k. Ann Rheum Dis. 2012 Nov;71(11):1904-8. doi: 10.1136/annrheumdis-2012-201746. Epub 2012 Aug 17. Ann Rheum Dis. 2012. PMID: 22904261
Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis.
Krämer M, Dees C, Huang J, Schlottmann I, Palumbo-Zerr K, Zerr P, Gelse K, Beyer C, Distler A, Marquez VE, Distler O, Schett G, Distler JH. Krämer M, et al. Among authors: gelse k. Ann Rheum Dis. 2013 Apr;72(4):614-20. doi: 10.1136/annrheumdis-2012-201615. Epub 2012 Aug 21. Ann Rheum Dis. 2013. PMID: 22915621
Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis.
Beyer C, Reichert H, Akan H, Mallano T, Schramm A, Dees C, Palumbo-Zerr K, Lin NY, Distler A, Gelse K, Varga J, Distler O, Schett G, Distler JH. Beyer C, et al. Among authors: gelse k. Ann Rheum Dis. 2013 Jul;72(7):1255-8. doi: 10.1136/annrheumdis-2012-202544. Epub 2013 Apr 17. Ann Rheum Dis. 2013. PMID: 23595143
Signature of circulating microRNAs in osteoarthritis.
Beyer C, Zampetaki A, Lin NY, Kleyer A, Perricone C, Iagnocco A, Distler A, Langley SR, Gelse K, Sesselmann S, Lorenzini R, Niemeier A, Swoboda B, Distler JH, Santer P, Egger G, Willeit J, Mayr M, Schett G, Kiechl S. Beyer C, et al. Among authors: gelse k. Ann Rheum Dis. 2015 Mar;74(3):e18. doi: 10.1136/annrheumdis-2013-204698. Epub 2014 Feb 10. Ann Rheum Dis. 2015. PMID: 24515954
93 results