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A Dual Role of Upper Zone of Growth Plate and Cartilage Matrix-Associated Protein in Human and Mouse Osteoarthritic Cartilage: Inhibition of Aggrecanases and Promotion of Bone Turnover.
Stock M, Menges S, Eitzinger N, Geßlein M, Botschner R, Wormser L, Distler A, Schlötzer-Schrehardt U, Dietel K, Distler J, Beyer C, Gelse K, Engelke K, Koenders MI, van den Berg W, von der Mark K, Schett G. Stock M, et al. Among authors: gelse k. Arthritis Rheumatol. 2017 Jun;69(6):1233-1245. doi: 10.1002/art.40042. Epub 2017 Apr 24. Arthritis Rheumatol. 2017. PMID: 28086000
Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis.
Beyer C, Reichert H, Akan H, Mallano T, Schramm A, Dees C, Palumbo-Zerr K, Lin NY, Distler A, Gelse K, Varga J, Distler O, Schett G, Distler JH. Beyer C, et al. Among authors: gelse k. Ann Rheum Dis. 2013 Jul;72(7):1255-8. doi: 10.1136/annrheumdis-2012-202544. Epub 2013 Apr 17. Ann Rheum Dis. 2013. PMID: 23595143
Inhibition of sumoylation prevents experimental fibrosis.
Khodzhigorova A, Distler A, Lang V, Dees C, Schneider H, Beyer C, Gelse K, Distler O, Schett G, Distler JH. Khodzhigorova A, et al. Among authors: gelse k. Ann Rheum Dis. 2012 Nov;71(11):1904-8. doi: 10.1136/annrheumdis-2012-201746. Epub 2012 Aug 17. Ann Rheum Dis. 2012. PMID: 22904261
β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.
Beyer C, Schramm A, Akhmetshina A, Dees C, Kireva T, Gelse K, Sonnylal S, de Crombrugghe B, Taketo MM, Distler O, Schett G, Distler JH. Beyer C, et al. Among authors: gelse k. Ann Rheum Dis. 2012 May;71(5):761-7. doi: 10.1136/annrheumdis-2011-200568. Epub 2012 Feb 10. Ann Rheum Dis. 2012. PMID: 22328737 Free PMC article.
Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis.
Krämer M, Dees C, Huang J, Schlottmann I, Palumbo-Zerr K, Zerr P, Gelse K, Beyer C, Distler A, Marquez VE, Distler O, Schett G, Distler JH. Krämer M, et al. Among authors: gelse k. Ann Rheum Dis. 2013 Apr;72(4):614-20. doi: 10.1136/annrheumdis-2012-201615. Epub 2012 Aug 21. Ann Rheum Dis. 2013. PMID: 22915621
Signature of circulating microRNAs in osteoarthritis.
Beyer C, Zampetaki A, Lin NY, Kleyer A, Perricone C, Iagnocco A, Distler A, Langley SR, Gelse K, Sesselmann S, Lorenzini R, Niemeier A, Swoboda B, Distler JH, Santer P, Egger G, Willeit J, Mayr M, Schett G, Kiechl S. Beyer C, et al. Among authors: gelse k. Ann Rheum Dis. 2015 Mar;74(3):e18. doi: 10.1136/annrheumdis-2013-204698. Epub 2014 Feb 10. Ann Rheum Dis. 2015. PMID: 24515954
93 results