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Reducing biopharmaceutical manufacturing costs through continuous processing in a flexible J.POD® facility.
Drug Discov Today. 2023 Jul;28(7):103619. doi: 10.1016/j.drudis.2023.103619. Epub 2023 May 16.
Drug Discov Today. 2023.
PMID: 37201779
Free article.
Use of MMV as a Single Worst-Case Model Virus in Viral Filter Validation Studies.
Gefroh E, Dehghani H, McClure M, Connell-Crowley L, Vedantham G.
Gefroh E, et al.
PDA J Pharm Sci Technol. 2014 May-Jun;68(3):297-311. doi: 10.5731/pdajpst.2014.00978.
PDA J Pharm Sci Technol. 2014.
PMID: 25188350
Review.
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An alternate diafiltration strategy to mitigate protein precipitation for low solubility proteins.
Gefroh E, Lutz H.
Gefroh E, et al.
Biotechnol Prog. 2014 May-Jun;30(3):646-55. doi: 10.1002/btpr.1872. Epub 2014 Feb 1.
Biotechnol Prog. 2014.
PMID: 24449613
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Multipronged approach to managing beta-glucan contaminants in the downstream process: control of raw materials and filtration with charge-modified nylon 6,6 membrane filters.
Gefroh E, Hewig A, Vedantham G, McClure M, Krivosheyeva A, Lajmi A, Lu Y.
Gefroh E, et al.
Biotechnol Prog. 2013 May-Jun;29(3):672-80. doi: 10.1002/btpr.1718. Epub 2013 Apr 18.
Biotechnol Prog. 2013.
PMID: 23596143
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Recovery modeling of tangential flow systems.
Rao S, Gefroh E, Kaltenbrunner O.
Rao S, et al. Among authors: gefroh e.
Biotechnol Bioeng. 2012 Dec;109(12):3084-92. doi: 10.1002/bit.24577. Epub 2012 Jun 27.
Biotechnol Bioeng. 2012.
PMID: 22688788
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Qualification of a novel inline spiking method for virus filter validation.
Lutz H, Chang W, Blandl T, Ramsey G, Parella J, Fisher J, Gefroh E.
Lutz H, et al. Among authors: gefroh e.
Biotechnol Prog. 2011 Jan-Feb;27(1):121-8. doi: 10.1002/btpr.500. Epub 2010 Sep 27.
Biotechnol Prog. 2011.
PMID: 20878721
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