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Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression.
Al-Dabet MM, Shahzad K, Elwakiel A, Sulaj A, Kopf S, Bock F, Gadi I, Zimmermann S, Rana R, Krishnan S, Gupta D, Manoharan J, Fatima S, Nazir S, Schwab C, Baber R, Scholz M, Geffers R, Mertens PR, Nawroth PP, Griffin JH, Keller M, Dockendorff C, Kohli S, Isermann B. Al-Dabet MM, et al. Among authors: geffers r. Nat Commun. 2022 Aug 27;13(1):5062. doi: 10.1038/s41467-022-32477-9. Nat Commun. 2022. PMID: 36030260 Free PMC article.
Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1.
Bernhardt A, Fehr A, Brandt S, Jerchel S, Ballhause TM, Philipsen L, Stolze S, Geffers R, Weng H, Fischer KD, Isermann B, Brunner-Weinzierl MC, Batra A, Siegmund B, Zhu C, Lindquist JA, Mertens PR. Bernhardt A, et al. Among authors: geffers r. Kidney Int. 2017 Nov;92(5):1157-1177. doi: 10.1016/j.kint.2017.03.035. Epub 2017 Jun 11. Kidney Int. 2017. PMID: 28610763 Free article.
Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression.
Brandt S, Ballhause TM, Bernhardt A, Becker A, Salaru D, Le-Deffge HM, Fehr A, Fu Y, Philipsen L, Djudjaj S, Müller AJ, Kramann R, Ibrahim M, Geffers R, Siebel C, Isermann B, Heidel FH, Lindquist JA, Mertens PR. Brandt S, et al. Among authors: geffers r. J Am Soc Nephrol. 2020 Nov;31(11):2589-2608. doi: 10.1681/ASN.2019121289. Epub 2020 Aug 28. J Am Soc Nephrol. 2020. PMID: 32859670 Free PMC article.
Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently.
Gadi I, Fatima S, Elwakiel A, Nazir S, Mohanad Al-Dabet M, Rana R, Bock F, Manoharan J, Gupta D, Biemann R, Nieswandt B, Braun-Dullaeus R, Besler C, Scholz M, Geffers R, Griffin JH, Esmon CT, Kohli S, Isermann B, Shahzad K. Gadi I, et al. Among authors: geffers r. Circ Res. 2021 Feb 19;128(4):513-529. doi: 10.1161/CIRCRESAHA.120.317219. Epub 2020 Dec 23. Circ Res. 2021. PMID: 33353373 Free PMC article.
p21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury.
Marhenke S, Buitrago-Molina LE, Endig J, Orlik J, Schweitzer N, Klett S, Longerich T, Geffers R, Sánchez Muñoz A, Dorrell C, Katz SF, Lechel A, Weng H, Krech T, Lehmann U, Dooley S, Rudolph KL, Manns MP, Vogel A. Marhenke S, et al. Among authors: geffers r. Gut. 2014 Sep;63(9):1501-12. doi: 10.1136/gutjnl-2013-304829. Epub 2013 Oct 3. Gut. 2014. PMID: 24092862
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection.
Tang BM, Shojaei M, Teoh S, Meyers A, Ho J, Ball TB, Keynan Y, Pisipati A, Kumar A, Eisen DP, Lai K, Gillett M, Santram R, Geffers R, Schreiber J, Mozhui K, Huang S, Parnell GP, Nalos M, Holubova M, Chew T, Booth D, Kumar A, McLean A, Schughart K. Tang BM, et al. Among authors: geffers r. Nat Commun. 2019 Jul 31;10(1):3422. doi: 10.1038/s41467-019-11249-y. Nat Commun. 2019. PMID: 31366921 Free PMC article.
301 results