Geffers R - Search Results

1

Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.

He W, Henne A, Lauterbach M, Geißmar E, Nikolka F, Kho C, Heinz A, Dostert C, Grusdat M, Cordes T, Härm J, Goldmann O, Ewen A, Verschueren C, Blay-Cadanet J, Geffers R, Garritsen H, Kneiling M, Holm CK, Metallo CM, Medina E, Abdullah Z, Latz E, Brenner D, Hiller K. He W, et al. Among authors: geffers r. Nat Metab. 2022 May;4(5):524-533. doi: 10.1038/s42255-022-00565-1. Epub 2022 Jun 2. Nat Metab. 2022. PMID: 35655024 Free PMC article.

2

The role of the MHC on resistance to group a streptococci in mice.

Goldmann O, Lengeling A, Böse J, Bloecker H, Geffers R, Chhatwal GS, Medina E. Goldmann O, et al. Among authors: geffers r. J Immunol. 2005 Sep 15;175(6):3862-72. doi: 10.4049/jimmunol.175.6.3862. J Immunol. 2005. PMID: 16148132

3

Transcriptome analysis of murine macrophages in response to infection with Streptococcus pyogenes reveals an unusual activation program.

Goldmann O, von Köckritz-Blickwede M, Höltje C, Chhatwal GS, Geffers R, Medina E. Goldmann O, et al. Among authors: geffers r. Infect Immun. 2007 Aug;75(8):4148-57. doi: 10.1128/IAI.00181-07. Epub 2007 May 25. Infect Immun. 2007. PMID: 17526748 Free PMC article.

4

The dynamics of T cells during persistent Staphylococcus aureus infection: from antigen-reactivity to in vivo anergy.

Ziegler C, Goldmann O, Hobeika E, Geffers R, Peters G, Medina E. Ziegler C, et al. Among authors: geffers r. EMBO Mol Med. 2011 Nov;3(11):652-66. doi: 10.1002/emmm.201100173. Epub 2011 Sep 2. EMBO Mol Med. 2011. PMID: 21887823 Free PMC article.

5

Impairment of neuronal mitochondrial function by L-DOPA in the absence of oxygen-dependent auto-oxidation and oxidative cell damage.

Hörmann P, Delcambre S, Hanke J, Geffers R, Leist M, Hiller K. Hörmann P, et al. Among authors: geffers r. Cell Death Discov. 2021 Jun 28;7(1):151. doi: 10.1038/s41420-021-00547-4. Cell Death Discov. 2021. PMID: 34226525 Free PMC article.

6

Dysregulated Immunometabolism Is Associated with the Generation of Myeloid-Derived Suppressor Cells in Staphylococcus aureus Chronic Infection.

Dietrich O, Heinz A, Goldmann O, Geffers R, Beineke A, Hiller K, Saliba AE, Medina E. Dietrich O, et al. Among authors: geffers r. J Innate Immun. 2022;14(3):257-274. doi: 10.1159/000519306. Epub 2021 Nov 11. J Innate Immun. 2022. PMID: 34763332 Free PMC article.

7

Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection.

Sohail A, Iqbal AA, Sahini N, Chen F, Tantawy M, Waqas SFH, Winterhoff M, Ebensen T, Schultz K, Geffers R, Schughart K, Preusse M, Shehata M, Bähre H, Pils MC, Guzman CA, Mostafa A, Pleschka S, Falk C, Michelucci A, Pessler F. Sohail A, et al. Among authors: geffers r. PLoS Pathog. 2022 Jan 13;18(1):e1010219. doi: 10.1371/journal.ppat.1010219. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35025971 Free PMC article.

8

IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model.

Lonnemann N, Hosseini S, Ohm M, Geffers R, Hiller K, Dinarello CA, Korte M. Lonnemann N, et al. Among authors: geffers r. Elife. 2022 Aug 30;11:e75889. doi: 10.7554/eLife.75889. Elife. 2022. PMID: 36040311 Free PMC article.

9

YB-1 Interferes with TNFα-TNFR Binding and Modulates Progranulin-Mediated Inhibition of TNFα Signaling.

Hessman CL, Hildebrandt J, Shah A, Brandt S, Bock A, Frye BC, Raffetseder U, Geffers R, Brunner-Weinzierl MC, Isermann B, Mertens PR, Lindquist JA. Hessman CL, et al. Among authors: geffers r. Int J Mol Sci. 2020 Sep 25;21(19):7076. doi: 10.3390/ijms21197076. Int J Mol Sci. 2020. PMID: 32992926 Free PMC article.

10

ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives.

Waqas SF, Sohail A, Nguyen AHH, Usman A, Ludwig T, Wegner A, Malik MNH, Schuchardt S, Geffers R, Winterhoff M, Merkert S, Martin U, Olmer R, Lachmann N, Pessler F. Waqas SF, et al. Among authors: geffers r. Clin Transl Med. 2022 Jul;12(7):e931. doi: 10.1002/ctm2.931. Clin Transl Med. 2022. PMID: 35842904 Free PMC article.

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