Gearhart MD - Search Results

1

Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs.

Junco SE, Wang R, Gaipa JC, Taylor AB, Schirf V, Gearhart MD, Bardwell VJ, Demeler B, Hart PJ, Kim CA. Junco SE, et al. Among authors: gearhart md. Structure. 2013 Apr 2;21(4):665-71. doi: 10.1016/j.str.2013.02.013. Epub 2013 Mar 21. Structure. 2013. PMID: 23523425 Free PMC article.

2

Mitochondrial citrate metabolism and efflux regulate BeWo differentiation.

Mahr RM, Jena S, Nashif SK, Nelson AB, Rauckhorst AJ, Rome FI, Sheldon RD, Hughey CC, Puchalska P, Gearhart MD, Taylor EB, Crawford PA, Wernimont SA. Mahr RM, et al. Among authors: gearhart md. Sci Rep. 2023 May 6;13(1):7387. doi: 10.1038/s41598-023-34435-x. Sci Rep. 2023. PMID: 37149697 Free PMC article.

3

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.

Bosnakovski D, Toso EA, Ener ET, Gearhart MD, Yin L, Lüttmann FF, Magli A, Shi K, Kim J, Aihara H, Kyba M. Bosnakovski D, et al. Among authors: gearhart md. iScience. 2023 Sep 2;26(10):107823. doi: 10.1016/j.isci.2023.107823. eCollection 2023 Oct 20. iScience. 2023. PMID: 37744032 Free PMC article.

4

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.

Bosnakovski D, Toso EA, Ener ET, Gearhart MD, Yin L, Lüttmann FF, Magli A, Shi K, Kim J, Aihara H, Kyba M. Bosnakovski D, et al. Among authors: gearhart md. bioRxiv [Preprint]. 2023 Jan 22:2023.01.21.524976. doi: 10.1101/2023.01.21.524976. bioRxiv. 2023. PMID: 36711898 Free PMC article. Updated. Preprint.

5

Metformin impairs trophoblast metabolism and differentiation in dose dependent manner.

Nashif SK, Mahr RM, Jena S, Jo S, Nelson AB, Sadowski D, Crawford PA, Puchalska P, Alejandro EU, Gearhart MD, Wernimont SA. Nashif SK, et al. Among authors: gearhart md. bioRxiv [Preprint]. 2023 Feb 17:2023.02.14.528531. doi: 10.1101/2023.02.14.528531. bioRxiv. 2023. PMID: 36824783 Free PMC article. Updated. Preprint.

6

Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm.

Pappas MP, Kawakami H, Corcoran D, Chen KQ, Scott EP, Wong J, Gearhart MD, Nishinakamura R, Nakagawa Y, Kawakami Y. Pappas MP, et al. Among authors: gearhart md. Development. 2024 Mar 1;151(5):dev202649. doi: 10.1242/dev.202649. Epub 2024 Mar 4. Development. 2024. PMID: 38345319 Free PMC article.

7

Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets.

Gearhart MD, Corcoran CM, Wamstad JA, Bardwell VJ. Gearhart MD, et al. Mol Cell Biol. 2006 Sep;26(18):6880-9. doi: 10.1128/MCB.00630-06. Mol Cell Biol. 2006. PMID: 16943429 Free PMC article.

8

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.

Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD Jr, Xue F, Mason CE, Hiebert SW, Prive GG, Cerchietti L, Bardwell VJ, Elemento O, Melnick A. Hatzi K, et al. Among authors: gearhart md. Cell Rep. 2013 Aug 15;4(3):578-88. doi: 10.1016/j.celrep.2013.06.016. Epub 2013 Aug 1. Cell Rep. 2013. PMID: 23911289 Free PMC article.

9

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis.

Zhang T, Murphy MW, Gearhart MD, Bardwell VJ, Zarkower D. Zhang T, et al. Among authors: gearhart md. Development. 2014 Oct;141(19):3662-71. doi: 10.1242/dev.113936. Development. 2014. PMID: 25249458 Free PMC article.

10

Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function.

Yang JA, Tubo NJ, Gearhart MD, Bardwell VJ, Jenkins MK. Yang JA, et al. Among authors: gearhart md. J Immunol. 2015 Jun 15;194(12):5604-8. doi: 10.4049/jimmunol.1500201. Epub 2015 May 11. J Immunol. 2015. PMID: 25964495 Free PMC article.

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