Ge EJ - Search Results

1

Connecting copper and cancer: from transition metal signalling to metalloplasia.

Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LT, Van Aelst L, Xi D, Yuan P, Brady DC, Chang CJ. Ge EJ, et al. Nat Rev Cancer. 2022 Feb;22(2):102-113. doi: 10.1038/s41568-021-00417-2. Epub 2021 Nov 11. Nat Rev Cancer. 2022. PMID: 34764459 Free PMC article. Review.

2

Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates.

Toh JDW, Crossley SWM, Bruemmer KJ, Ge EJ, He D, Iovan DA, Chang CJ. Toh JDW, et al. Among authors: ge ej. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25284-25292. doi: 10.1073/pnas.2007349117. Epub 2020 Sep 28. Proc Natl Acad Sci U S A. 2020. PMID: 32989163 Free PMC article.

3

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine.

Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H. Jiang H, et al. Nature. 2013 Apr 4;496(7443):110-3. doi: 10.1038/nature12038. Nature. 2013. PMID: 23552949 Free PMC article.

4

Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism.

Pham VN, Bruemmer KJ, Toh JDW, Ge EJ, Tenney L, Ward CC, Dingler FA, Millington CL, Garcia-Prieto CA, Pulos-Holmes MC, Ingolia NT, Pontel LB, Esteller M, Patel KJ, Nomura DK, Chang CJ. Pham VN, et al. Among authors: ge ej. Science. 2023 Nov 3;382(6670):eabp9201. doi: 10.1126/science.abp9201. Epub 2023 Nov 3. Science. 2023. PMID: 37917677

5

Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase.

Jani KS, Jain SU, Ge EJ, Diehl KL, Lundgren SM, Müller MM, Lewis PW, Muir TW. Jani KS, et al. Among authors: ge ej. Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8295-8300. doi: 10.1073/pnas.1819029116. Epub 2019 Apr 9. Proc Natl Acad Sci U S A. 2019. PMID: 30967505 Free PMC article.

6

PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.

Diehl KL, Ge EJ, Weinberg DN, Jani KS, Allis CD, Muir TW. Diehl KL, et al. Among authors: ge ej. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22152-22157. doi: 10.1073/pnas.1911775116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611394 Free PMC article.

7

Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin.

Leicher R, Ge EJ, Lin X, Reynolds MJ, Xie W, Walz T, Zhang B, Muir TW, Liu S. Leicher R, et al. Among authors: ge ej. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30465-30475. doi: 10.1073/pnas.2003395117. Epub 2020 Nov 18. Proc Natl Acad Sci U S A. 2020. PMID: 33208532 Free PMC article.

8

Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate.

Oslund RC, Su X, Haugbro M, Kee JM, Esposito M, David Y, Wang B, Ge E, Perlman DH, Kang Y, Muir TW, Rabinowitz JD. Oslund RC, et al. Nat Chem Biol. 2017 Oct;13(10):1081-1087. doi: 10.1038/nchembio.2453. Epub 2017 Aug 7. Nat Chem Biol. 2017. PMID: 28805803 Free PMC article.

9

Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.

Wang X, Paucek RD, Gooding AR, Brown ZZ, Ge EJ, Muir TW, Cech TR. Wang X, et al. Among authors: ge ej. Nat Struct Mol Biol. 2017 Dec;24(12):1028-1038. doi: 10.1038/nsmb.3487. Epub 2017 Oct 23. Nat Struct Mol Biol. 2017. PMID: 29058709 Free PMC article.

10

Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric Constraints and Impact of the Regulatory Subunit JARID2.

Ge EJ, Jani KS, Diehl KL, Müller MM, Muir TW. Ge EJ, et al. J Am Chem Soc. 2019 Sep 25;141(38):15029-15039. doi: 10.1021/jacs.9b02321. Epub 2019 Sep 17. J Am Chem Soc. 2019. PMID: 31479253 Free PMC article.

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