Gazdik M - Search Results

1

Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei.

Ferrins L, Gazdik M, Rahmani R, Varghese S, Sykes ML, Jones AJ, Avery VM, White KL, Ryan E, Charman SA, Kaiser M, Bergström CA, Baell JB. Ferrins L, et al. Among authors: gazdik m. J Med Chem. 2014 Aug 14;57(15):6393-402. doi: 10.1021/jm500191u. Epub 2014 Jul 17. J Med Chem. 2014. PMID: 24978605

2

Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions.

Lee J, Vinh NB, Drinkwater N, Yang W, Kannan Sivaraman K, Schembri LS, Gazdik M, Grin PM, Butler GS, Overall CM, Charman SA, McGowan S, Scammells PJ. Lee J, et al. Among authors: gazdik m. J Med Chem. 2019 Aug 8;62(15):7185-7209. doi: 10.1021/acs.jmedchem.9b00757. Epub 2019 Jul 18. J Med Chem. 2019. PMID: 31251594

3

Transition state mimetics of the Plasmodium export element are potent inhibitors of Plasmepsin V from P. falciparum and P. vivax.

Sleebs BE, Gazdik M, O'Neill MT, Rajasekaran P, Lopaticki S, Lackovic K, Lowes K, Smith BJ, Cowman AF, Boddey JA. Sleebs BE, et al. Among authors: gazdik m. J Med Chem. 2014 Sep 25;57(18):7644-62. doi: 10.1021/jm500797g. Epub 2014 Sep 11. J Med Chem. 2014. PMID: 25167370

4

Exploration of the P3 region of PEXEL peptidomimetics leads to a potent inhibitor of the Plasmodium protease, plasmepsin V.

Gazdik M, Jarman KE, O'Neill MT, Hodder AN, Lowes KN, Jousset Sabroux H, Cowman AF, Boddey JA, Sleebs BE. Gazdik M, et al. Bioorg Med Chem. 2016 May 1;24(9):1993-2010. doi: 10.1016/j.bmc.2016.03.027. Epub 2016 Mar 16. Bioorg Med Chem. 2016. PMID: 27021426

5

Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes.

Hodder AN, Sleebs BE, Czabotar PE, Gazdik M, Xu Y, O'Neill MT, Lopaticki S, Nebl T, Triglia T, Smith BJ, Lowes K, Boddey JA, Cowman AF. Hodder AN, et al. Among authors: gazdik m. Nat Struct Mol Biol. 2015 Aug;22(8):590-6. doi: 10.1038/nsmb.3061. Epub 2015 Jul 27. Nat Struct Mol Biol. 2015. PMID: 26214367

6

Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.

Sleebs BE, Lopaticki S, Marapana DS, O'Neill MT, Rajasekaran P, Gazdik M, Günther S, Whitehead LW, Lowes KN, Barfod L, Hviid L, Shaw PJ, Hodder AN, Smith BJ, Cowman AF, Boddey JA. Sleebs BE, et al. Among authors: gazdik m. PLoS Biol. 2014 Jul 1;12(7):e1001897. doi: 10.1371/journal.pbio.1001897. eCollection 2014 Jul. PLoS Biol. 2014. PMID: 24983235 Free PMC article.

7

Prediction of Bloodstream Infection Due to Vancomycin-Resistant Enterococcus in Patients Undergoing Leukemia Induction or Hematopoietic Stem-Cell Transplantation.

Webb BJ, Healy R, Majers J, Burr Z, Gazdik M, Lopansri B, Hoda D, Petersen FB, Ford C. Webb BJ, et al. Among authors: gazdik m. Clin Infect Dis. 2017 Jun 15;64(12):1753-1759. doi: 10.1093/cid/cix232. Clin Infect Dis. 2017. PMID: 28369204

8

Vancomycin-Resistant Enterococcus Colonization and Bacteremia and Hematopoietic Stem Cell Transplantation Outcomes.

Ford CD, Gazdik MA, Lopansri BK, Webb B, Mitchell B, Coombs J, Hoda D, Petersen FB. Ford CD, et al. Among authors: gazdik ma. Biol Blood Marrow Transplant. 2017 Feb;23(2):340-346. doi: 10.1016/j.bbmt.2016.11.017. Epub 2016 Nov 23. Biol Blood Marrow Transplant. 2017. PMID: 27890428 Free article.

9

Room contamination, patient colonization pressure, and the risk of vancomycin-resistant Enterococcus colonization on a unit dedicated to the treatment of hematologic malignancies and hematopoietic stem cell transplantation.

Ford CD, Lopansri BK, Gazdik MA, Webb B, Snow GL, Hoda D, Adams B, Petersen FB. Ford CD, et al. Among authors: gazdik ma. Am J Infect Control. 2016 Oct 1;44(10):1110-1115. doi: 10.1016/j.ajic.2016.03.044. Epub 2016 Jun 7. Am J Infect Control. 2016. PMID: 27287734

10

Fecal microbiota transplantation for recurrent Clostridium difficile infection in hematopoietic stem cell transplant recipients.

Webb BJ, Brunner A, Ford CD, Gazdik MA, Petersen FB, Hoda D. Webb BJ, et al. Among authors: gazdik ma. Transpl Infect Dis. 2016 Aug;18(4):628-33. doi: 10.1111/tid.12550. Epub 2016 Jul 5. Transpl Infect Dis. 2016. PMID: 27214585 Clinical Trial.

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