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The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming.
Sardinha-Silva A, Mendonça-Natividade FC, Pinzan CF, Lopes CD, Costa DL, Jacot D, Fernandes FF, Zorzetto-Fernandes ALV, Gay NJ, Sher A, Jankovic D, Soldati-Favre D, Grigg ME, Roque-Barreira MC. Sardinha-Silva A, et al. Among authors: gay nj. PLoS Pathog. 2019 Jun 21;15(6):e1007871. doi: 10.1371/journal.ppat.1007871. eCollection 2019 Jun. PLoS Pathog. 2019. PMID: 31226171 Free PMC article.
Therapeutic administration of recombinant Paracoccin confers protection against paracoccidioides brasiliensis infection: involvement of TLRs.
Alegre-Maller AC, Mendonça FC, da Silva TA, Oliveira AF, Freitas MS, Hanna ES, Almeida IC, Gay NJ, Roque-Barreira MC. Alegre-Maller AC, et al. Among authors: gay nj. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3317. doi: 10.1371/journal.pntd.0003317. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25474158 Free PMC article.
Yeast expressed ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM.
Cecílio NT, Carvalho FC, Liu Y, Moncrieffe M, Buranello PA, Zorzetto-Fernandes AL, Luche DD, Hanna ES, Soares SG, Feizi T, Gay NJ, Goldman MH, Roque-Barreira MC. Cecílio NT, et al. Among authors: gay nj. Int J Biol Macromol. 2016 Jan;82:22-30. doi: 10.1016/j.ijbiomac.2015.09.062. Epub 2015 Oct 1. Int J Biol Macromol. 2016. PMID: 26433176 Free article.
Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis.
Fels Elliott DR, Perner J, Li X, Symmons MF, Verstak B, Eldridge M, Bower L, O'Donovan M, Gay NJ; OCCAMS Consortium; Fitzgerald RC. Fels Elliott DR, et al. Among authors: gay nj. PLoS Genet. 2017 May 22;13(5):e1006808. doi: 10.1371/journal.pgen.1006808. eCollection 2017 May. PLoS Genet. 2017. PMID: 28531216 Free PMC article.
204 results