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Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
Falcinelli SD, Peterson JJ, Turner AW, Irlbeck D, Read J, Raines SL, James KS, Sutton C, Sanchez A, Emery A, Sampey G, Ferris R, Allard B, Ghofrani S, Kirchherr JL, Baker C, Kuruc JD, Gay CL, James LI, Wu G, Zuck P, Rioja I, Furze RC, Prinjha RK, Howell BJ, Swanstrom R, Browne EP, Strahl BD, Dunham RM, Archin NM, Margolis DM. Falcinelli SD, et al. Among authors: gay cl. J Clin Invest. 2022 Apr 15;132(8):e157281. doi: 10.1172/JCI157281. J Clin Invest. 2022. PMID: 35426377 Free PMC article.
Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection.
Gay CL, Mayo AJ, Mfalila CK, Chu H, Barry AC, Kuruc JD, McGee KS, Kerkau M, Sebastian J, Fiscus SA, Margolis DM, Hicks CB, Ferrari G, Eron JJ; Duke-UNC Acute HIV Infection Consortium. Gay CL, et al. AIDS. 2011 Apr 24;25(7):941-9. doi: 10.1097/QAD.0b013e3283463c07. AIDS. 2011. PMID: 21487250 Free PMC article.
Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection.
Archin NM, Vaidya NK, Kuruc JD, Liberty AL, Wiegand A, Kearney MF, Cohen MS, Coffin JM, Bosch RJ, Gay CL, Eron JJ, Margolis DM, Perelson AS. Archin NM, et al. Among authors: gay cl. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9523-8. doi: 10.1073/pnas.1120248109. Epub 2012 May 29. Proc Natl Acad Sci U S A. 2012. PMID: 22645358 Free PMC article.
Acute HIV-1 infection in the Southeastern United States: a cohort study.
McKellar MS, Cope AB, Gay CL, McGee KS, Kuruc JD, Kerkau MG, Hurt CB, Fiscus SA, Ferrari G, Margolis DM, Eron JJ, Hicks CB; Duke-Unc Acute HIV Infection Consortium. McKellar MS, et al. Among authors: gay cl. AIDS Res Hum Retroviruses. 2013 Jan;29(1):121-8. doi: 10.1089/aid.2012.0064. Epub 2012 Sep 4. AIDS Res Hum Retroviruses. 2013. PMID: 22839749 Free PMC article.
204 results