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Page 1
Potent Lys Patch-Containing Stapled Peptides Targeting PCSK9.
Bourbiaux K, Legrand B, Verdié P, Mallart S, Manette G, Minoletti C, Stepp JD, Prigent P, Le Bail JC, Gauzy-Lazo L, Duclos O, Martinez J, Amblard M. Bourbiaux K, et al. Among authors: gauzy lazo l. J Med Chem. 2021 Aug 12;64(15):10834-10848. doi: 10.1021/acs.jmedchem.0c02051. Epub 2021 Jul 15. J Med Chem. 2021. PMID: 34266235
Identification of Potent and Long-Acting Single-Chain Peptide Mimetics of Human Relaxin-2 for Cardiovascular Diseases.
Mallart S, Ingenito R, Bianchi E, Bresciani A, Esposito S, Gallo M, Magotti P, Monteagudo E, Orsatti L, Roversi D, Santoprete A, Tucci F, Veneziano M, Bartsch R, Boehm C, Brasseur D, Bruneau P, Corbier A, Froissant J, Gauzy-Lazo L, Gervat V, Marguet F, Menguy I, Minoletti C, Nicolas MF, Pasquier O, Poirier B, Raux A, Riva L, Janiak P, Strobel H, Duclos O, Illiano S. Mallart S, et al. Among authors: gauzy lazo l. J Med Chem. 2021 Feb 25;64(4):2139-2150. doi: 10.1021/acs.jmedchem.0c01533. Epub 2021 Feb 8. J Med Chem. 2021. PMID: 33555858
Fatty acid acylated peptide therapeutics: discovery of omega-n oxidation of the lipid chain as a novel metabolic pathway in preclinical species.
Esposito S, Krick A, Pasquier O, Bonche F, Ingenito R, Magotti P, Bianchi E, Monteagudo E, Gallo M, Cicero DO, Orsatti L, Veneziano M, Caretti F, Mele R, Roversi D, Gennari N, Brasseur D, Gauzy-Lazo L, Duclos O, Mauriac C, Illiano S, Mallart S. Esposito S, et al. Among authors: gauzy lazo l. J Pharm Biomed Anal. 2023 Apr 1;227:115256. doi: 10.1016/j.jpba.2023.115256. Epub 2023 Jan 18. J Pharm Biomed Anal. 2023. PMID: 36764268
Protocols for lysine conjugation.
Brun MP, Gauzy-Lazo L. Brun MP, et al. Among authors: gauzy lazo l. Methods Mol Biol. 2013;1045:173-87. doi: 10.1007/978-1-62703-541-5_10. Methods Mol Biol. 2013. PMID: 23913147
R2R01: A long-acting single-chain peptide agonist of RXFP1 for renal and cardiovascular diseases.
Poirier B, Pasquier O, Chenede X, Corbier A, Prigent P, Azam A, Bernard C, Guillotel M, Gillot F, Riva L, Briand V, Ingenito R, Gauzy-Lazo L, Duclos O, Philippo C, Maillere B, Bianchi E, Mallart S, Janiak P, Illiano S. Poirier B, et al. Among authors: gauzy lazo l. Br J Pharmacol. 2024 Mar 7. doi: 10.1111/bph.16338. Online ahead of print. Br J Pharmacol. 2024. PMID: 38450758