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Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging.
Sola-García A, Cáliz-Molina MÁ, Espadas I, Petr M, Panadero-Morón C, González-Morán D, Martín-Vázquez ME, Narbona-Pérez ÁJ, López-Noriega L, Martínez-Corrales G, López-Fernández-Sobrino R, Carmona-Marin LM, Martínez-Force E, Yanes O, Vinaixa M, López-López D, Reyes JC, Dopazo J, Martín F, Gauthier BR, Scheibye-Knudsen M, Capilla-González V, Martín-Montalvo A. Sola-García A, et al. Among authors: gauthier br. Commun Biol. 2023 Mar 8;6(1):250. doi: 10.1038/s42003-023-04625-4. Commun Biol. 2023. PMID: 36890357 Free PMC article.
Thyroid hormones in diabetes, cancer, and aging.
Gauthier BR, Sola-García A, Cáliz-Molina MÁ, Lorenzo PI, Cobo-Vuilleumier N, Capilla-González V, Martin-Montalvo A. Gauthier BR, et al. Aging Cell. 2020 Nov;19(11):e13260. doi: 10.1111/acel.13260. Epub 2020 Oct 13. Aging Cell. 2020. PMID: 33048427 Free PMC article. Review.
Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging.
López-Noriega L, Capilla-González V, Cobo-Vuilleumier N, Martin-Vazquez E, Lorenzo PI, Martinez-Force E, Soriano-Navarro M, García-Fernández M, Romero-Zerbo SY, Bermúdez-Silva FJ, Díaz-Contreras I, Sánchez-Cuesta A, Santos-Ocaña C, Hmadcha A, Soria B, Martín F, Gauthier BR, Martin-Montalvo A. López-Noriega L, et al. Among authors: gauthier br. Aging (Albany NY). 2019 Sep 13;11(18):7746-7779. doi: 10.18632/aging.102285. Epub 2019 Sep 13. Aging (Albany NY). 2019. PMID: 31518338 Free PMC article.
Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy.
Hmadcha A, Martin-Montalvo A, Gauthier BR, Soria B, Capilla-Gonzalez V. Hmadcha A, et al. Among authors: gauthier br. Front Bioeng Biotechnol. 2020 Feb 5;8:43. doi: 10.3389/fbioe.2020.00043. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 32117924 Free PMC article. Review.
The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity.
Lorenzo PI, Martin Vazquez E, López-Noriega L, Fuente-Martín E, Mellado-Gil JM, Franco JM, Cobo-Vuilleumier N, Guerrero Martínez JA, Romero-Zerbo SY, Perez-Cabello JA, Rivero Canalejo S, Campos-Caro A, Lachaud CC, Crespo Barreda A, Aguilar-Diosdado M, García Fuentes E, Martin-Montalvo A, Álvarez Dolado M, Martin F, Rojo-Martinez G, Pozo D, Bérmudez-Silva FJ, Comaills V, Reyes JC, Gauthier BR. Lorenzo PI, et al. Among authors: gauthier br. Theranostics. 2021 May 12;11(14):6983-7004. doi: 10.7150/thno.57237. eCollection 2021. Theranostics. 2021. PMID: 34093866 Free PMC article.
LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Cobo-Vuilleumier N, Lorenzo PI, Rodríguez NG, Herrera Gómez IG, Fuente-Martin E, López-Noriega L, Mellado-Gil JM, Romero-Zerbo SY, Baquié M, Lachaud CC, Stifter K, Perdomo G, Bugliani M, De Tata V, Bosco D, Parnaud G, Pozo D, Hmadcha A, Florido JP, Toscano MG, de Haan P, Schoonjans K, Sánchez Palazón L, Marchetti P, Schirmbeck R, Martín-Montalvo A, Meda P, Soria B, Bermúdez-Silva FJ, St-Onge L, Gauthier BR. Cobo-Vuilleumier N, et al. Among authors: gauthier br. Nat Commun. 2018 Apr 16;9(1):1488. doi: 10.1038/s41467-018-03943-0. Nat Commun. 2018. PMID: 29662071 Free PMC article.
83 results