Gauthier A - Search Results

1

A Standardized Botanical Composition Mitigated Acute Inflammatory Lung Injury and Reduced Mortality through Extracellular HMGB1 Reduction.

Yimam M, Horm T, O'Neal A, Jiao P, Hong M, Brownell L, Jia Q, Lin M, Gauthier A, Wu J, Venkat Mateti K, Yang X, Dial K, Zefi S, Mantell LL. Yimam M, et al. Among authors: gauthier a. Molecules. 2023 Sep 11;28(18):6560. doi: 10.3390/molecules28186560. Molecules. 2023. PMID: 37764336 Free PMC article.

2

The Role of HMGB1, a Nuclear Damage-Associated Molecular Pattern Molecule, in the Pathogenesis of Lung Diseases.

Wang M, Gauthier A, Daley L, Dial K, Wu J, Woo J, Lin M, Ashby C, Mantell LL. Wang M, et al. Among authors: gauthier a. Antioxid Redox Signal. 2019 Nov 1;31(13):954-993. doi: 10.1089/ars.2019.7818. Epub 2019 Jul 11. Antioxid Redox Signal. 2019. PMID: 31184204 Free PMC article. Review.

3

The nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (DETA-NONOate/D-NO), increases survival by attenuating hyperoxia-compromised innate immunity in bacterial clearance in a mouse model of ventilator-associated pneumonia.

Gore A, Gauthier AG, Lin M, Patel V, Thomas DD, Ashby CR Jr, Mantell LL. Gore A, et al. Among authors: gauthier ag. Biochem Pharmacol. 2020 Jun;176:113817. doi: 10.1016/j.bcp.2020.113817. Epub 2020 Jan 20. Biochem Pharmacol. 2020. PMID: 31972169 Free PMC article.

4

Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1.

Patel V, Dial K, Wu J, Gauthier AG, Wu W, Lin M, Espey MG, Thomas DD, Ashby CR Jr, Mantell LL. Patel V, et al. Int J Mol Sci. 2020 Feb 1;21(3):977. doi: 10.3390/ijms21030977. Int J Mol Sci. 2020. PMID: 32024151 Free PMC article.

5

The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation.

Sitapara RA, Gauthier AG, Valdés-Ferrer SI, Lin M, Patel V, Wang M, Martino AT, Perron JC, Ashby CR Jr, Tracey KJ, Pavlov VA, Mantell LL. Sitapara RA, et al. Among authors: gauthier ag. Mol Med. 2020 Jun 29;26(1):63. doi: 10.1186/s10020-020-00177-z. Mol Med. 2020. PMID: 32600307 Free PMC article.

6

The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.

Sitapara RA, Gauthier AG, Patel VS, Lin M, Zur M, Ashby CR Jr, Mantell LL. Sitapara RA, et al. Among authors: gauthier ag. Mol Med. 2020 Oct 30;26(1):98. doi: 10.1186/s10020-020-00224-9. Mol Med. 2020. PMID: 33126860 Free PMC article.

7

The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrophages.

Gauthier AG, Wu J, Lin M, Sitapara R, Kulkarni A, Thakur GA, Schmidt EE, Perron JC, Ashby CR Jr, Mantell LL. Gauthier AG, et al. Antioxidants (Basel). 2021 Jan 19;10(1):135. doi: 10.3390/antiox10010135. Antioxidants (Basel). 2021. PMID: 33477969 Free PMC article.

8

From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19?

Gauthier AG, Lin M, Wu J, Kennedy TP, Daley LA, Ashby CR Jr, Mantell LL. Gauthier AG, et al. J Immunotoxicol. 2021 Dec;18(1):23-29. doi: 10.1080/1547691X.2021.1875085. J Immunotoxicol. 2021. PMID: 33860730

9

2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function.

Wang M, Gauthier AG, Kennedy TP, Wang H, Velagapudi UK, Talele TT, Lin M, Wu J, Daley L, Yang X, Patel V, Mun SS, Ashby CR Jr, Mantell LL. Wang M, et al. Mol Med. 2021 Jul 16;27(1):79. doi: 10.1186/s10020-021-00334-y. Mol Med. 2021. PMID: 34271850 Free PMC article.

10

Correction to: GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.

Sitapara RA, Gauthier AG, Patel VS, Lin M, Zur M, Ashby CR Jr, Mantell LL. Sitapara RA, et al. Among authors: gauthier ag. Mol Med. 2021 Aug 23;27(1):93. doi: 10.1186/s10020-021-00357-5. Mol Med. 2021. PMID: 34425757 Free PMC article. No abstract available.

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