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Sequestration of a β-hairpin for control of α-synuclein aggregation.
Mirecka EA, Shaykhalishahi H, Gauhar A, Akgül Ş, Lecher J, Willbold D, Stoldt M, Hoyer W. Mirecka EA, et al. Among authors: gauhar a. Angew Chem Int Ed Engl. 2014 Apr 14;53(16):4227-30. doi: 10.1002/anie.201309001. Epub 2014 Mar 12. Angew Chem Int Ed Engl. 2014. PMID: 24623599
Functional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine finger.
Jaiswal M, Dvorsky R, Amin E, Risse SL, Fansa EK, Zhang SC, Taha MS, Gauhar AR, Nakhaei-Rad S, Kordes C, Koessmeier KT, Cirstea IC, Olayioye MA, Häussinger D, Ahmadian MR. Jaiswal M, et al. Among authors: gauhar ar. J Biol Chem. 2014 Mar 7;289(10):6839-6849. doi: 10.1074/jbc.M113.527655. Epub 2014 Jan 17. J Biol Chem. 2014. PMID: 24443565 Free PMC article.
A Single Domain Shark Antibody Targeting the Transferrin Receptor 1 Delivers a TrkB Agonist Antibody to the Brain and Provides Full Neuroprotection in a Mouse Model of Parkinson's Disease.
Clarke E, Stocki P, Sinclair EH, Gauhar A, Fletcher EJR, Krawczun-Rygmaczewska A, Duty S, Walsh FS, Doherty P, Rutkowski JL. Clarke E, et al. Among authors: gauhar a. Pharmaceutics. 2022 Jun 24;14(7):1335. doi: 10.3390/pharmaceutics14071335. Pharmaceutics. 2022. PMID: 35890231 Free PMC article.
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