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T cell activation is insufficient to drive SIV disease progression.
Apetrei C, Gaufin T, Brocca-Cofano E, Sivanandham R, Sette P, He T, Sivanandham S, Martinez Sosa N, Martin KJ, Raehtz KD, Kleinman AJ, Valentine A, Krampe N, Gautam R, Lackner AA, Landay AL, Ribeiro RM, Pandrea I. Apetrei C, et al. Among authors: gaufin t. JCI Insight. 2023 Jul 24;8(14):e161111. doi: 10.1172/jci.insight.161111. JCI Insight. 2023. PMID: 37485874 Free PMC article.
Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion.
Pandrea I, Gaufin T, Brenchley JM, Gautam R, Monjure C, Gautam A, Coleman C, Lackner AA, Ribeiro RM, Douek DC, Apetrei C. Pandrea I, et al. Among authors: gaufin t. J Immunol. 2008 Nov 15;181(10):6687-91. doi: 10.4049/jimmunol.181.10.6687. J Immunol. 2008. PMID: 18981083 Free PMC article.
Mucosal simian immunodeficiency virus transmission in African green monkeys: susceptibility to infection is proportional to target cell availability at mucosal sites.
Pandrea I, Parrish NF, Raehtz K, Gaufin T, Barbian HJ, Ma D, Kristoff J, Gautam R, Zhong F, Haret-Richter GS, Trichel A, Shaw GM, Hahn BH, Apetrei C. Pandrea I, et al. Among authors: gaufin t. J Virol. 2012 Apr;86(8):4158-68. doi: 10.1128/JVI.07141-11. Epub 2012 Feb 8. J Virol. 2012. PMID: 22318138 Free PMC article.
Simian immunodeficiency virus SIVagm dynamics in African green monkeys.
Pandrea I, Ribeiro RM, Gautam R, Gaufin T, Pattison M, Barnes M, Monjure C, Stoulig C, Dufour J, Cyprian W, Silvestri G, Miller MD, Perelson AS, Apetrei C. Pandrea I, et al. Among authors: gaufin t. J Virol. 2008 Apr;82(7):3713-24. doi: 10.1128/JVI.02402-07. Epub 2008 Jan 23. J Virol. 2008. PMID: 18216122 Free PMC article.
Simian immunodeficiency virus SIVrcm, a unique CCR2-tropic virus, selectively depletes memory CD4+ T cells in pigtailed macaques through expanded coreceptor usage in vivo.
Gautam R, Gaufin T, Butler I, Gautam A, Barnes M, Mandell D, Pattison M, Tatum C, Macfarland J, Monjure C, Marx PA, Pandrea I, Apetrei C. Gautam R, et al. Among authors: gaufin t. J Virol. 2009 Aug;83(16):7894-908. doi: 10.1128/JVI.00444-09. Epub 2009 Jun 3. J Virol. 2009. PMID: 19493994 Free PMC article.
19 results