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Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state.
Maté de Gérando A, d'Orange M, Augustin E, Joséphine C, Aurégan G, Gaudin-Guérif M, Guillermier M, Hérard AS, Stimmer L, Petit F, Gipchtein P, Jan C, Escartin C, Selingue E, Carvalho K, Blum D, Brouillet E, Hantraye P, Gaillard MC, Bonvento G, Bemelmans AP, Cambon K. Maté de Gérando A, et al. Among authors: gaudin guerif m. Brain. 2021 May 7;144(4):1167-1182. doi: 10.1093/brain/awab011. Brain. 2021. PMID: 33842937
Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat.
d'Orange M, Aurégan G, Cheramy D, Gaudin-Guérif M, Lieger S, Guillermier M, Stimmer L, Joséphine C, Hérard AS, Gaillard MC, Petit F, Kiessling MC, Schmitz C, Colin M, Buée L, Panayi F, Diguet E, Brouillet E, Hantraye P, Bemelmans AP, Cambon K. d'Orange M, et al. Among authors: gaudin guerif m. Brain. 2018 Feb 1;141(2):535-549. doi: 10.1093/brain/awx342. Brain. 2018. PMID: 29253129 Free PMC article.
Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway.
Abjean L, Ben Haim L, Riquelme-Perez M, Gipchtein P, Derbois C, Palomares MA, Petit F, Hérard AS, Gaillard MC, Guillermier M, Gaudin-Guérif M, Aurégan G, Sagar N, Héry C, Dufour N, Robil N, Kabani M, Melki R, De la Grange P, Bemelmans AP, Bonvento G, Deleuze JF, Hantraye P, Flament J, Bonnet E, Brohard S, Olaso R, Brouillet E, Carrillo-de Sauvage MA, Escartin C. Abjean L, et al. Among authors: gaudin guerif m. Brain. 2023 Jan 5;146(1):149-166. doi: 10.1093/brain/awac068. Brain. 2023. PMID: 35298632
Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease.
Le Douce J, Maugard M, Veran J, Matos M, Jégo P, Vigneron PA, Faivre E, Toussay X, Vandenberghe M, Balbastre Y, Piquet J, Guiot E, Tran NT, Taverna M, Marinesco S, Koyanagi A, Furuya S, Gaudin-Guérif M, Goutal S, Ghettas A, Pruvost A, Bemelmans AP, Gaillard MC, Cambon K, Stimmer L, Sazdovitch V, Duyckaerts C, Knott G, Hérard AS, Delzescaux T, Hantraye P, Brouillet E, Cauli B, Oliet SHR, Panatier A, Bonvento G. Le Douce J, et al. Among authors: gaudin guerif m. Cell Metab. 2020 Mar 3;31(3):503-517.e8. doi: 10.1016/j.cmet.2020.02.004. Cell Metab. 2020. PMID: 32130882 Free article.