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MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR.
Hergalant S, Casse JM, Oussalah A, Houlgatte R, Helle D, Rech F, Vallar L, Guéant JL, Vignaud JM, Battaglia-Hsu SF, Gauchotte G. Hergalant S, et al. Among authors: gauchotte g. Front Oncol. 2023 Aug 2;13:1158773. doi: 10.3389/fonc.2023.1158773. eCollection 2023. Front Oncol. 2023. PMID: 37601663 Free PMC article.
Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.
Gauchotte G, Hergalant S, Vigouroux C, Casse JM, Houlgatte R, Kaoma T, Helle D, Brochin L, Rech F, Peyre M, Labrousse F, Vallar L, Guéant JL, Vignaud JM, Battaglia-Hsu SF. Gauchotte G, et al. J Pathol. 2017 Aug;242(4):421-434. doi: 10.1002/path.4916. Epub 2017 Jul 5. J Pathol. 2017. PMID: 28493484
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Battaglia-Hsu SF, Ghemrawi R, Coelho D, Dreumont N, Mosca P, Hergalant S, Gauchotte G, Sequeira JM, Ndiongue M, Houlgatte R, Alberto JM, Umoret R, Robert A, Paoli J, Jung M, Quadros EV, Guéant JL. Battaglia-Hsu SF, et al. Among authors: gauchotte g. Nucleic Acids Res. 2018 Sep 6;46(15):7844-7857. doi: 10.1093/nar/gky634. Nucleic Acids Res. 2018. PMID: 30016500 Free PMC article.
Endothelial Cell Hypertrophy and Microvascular Proliferation in Meningiomas Are Correlated with Higher Histological Grade and Shorter Progression-Free Survival.
Ling C, Pouget C, Rech F, Pflaum R, Treffel M, Bielle F, Mokhtari K, Casse JM, Vignaud JM, Kalamarides M, Peyre M, Gauchotte G. Ling C, et al. Among authors: gauchotte g. J Neuropathol Exp Neurol. 2016 Dec 1;75(12):1160-1170. doi: 10.1093/jnen/nlw095. J Neuropathol Exp Neurol. 2016. PMID: 27807004
134 results