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Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia.
MacGregor Sharp M, Saito S, Keable A, Gatherer M, Aldea R, Agarwal N, Simpson JE, Wharton SB, Weller RO, Carare RO. MacGregor Sharp M, et al. Among authors: gatherer m. Acta Neuropathol Commun. 2020 Aug 8;8(1):131. doi: 10.1186/s40478-020-01009-1. Acta Neuropathol Commun. 2020. PMID: 32771063 Free PMC article.
The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix-significance for protein elimination failure arteriopathies.
Sharp MM, Cassidy J, Thornton T, Lyles J, Keable A, Gatherer M, Yasui M, Abe Y, Shibata S, Weller RO, Górecki DC, Carare RO. Sharp MM, et al. Among authors: gatherer m. Acta Neuropathol Commun. 2021 Oct 21;9(1):171. doi: 10.1186/s40478-021-01274-8. Acta Neuropathol Commun. 2021. PMID: 34674769 Free PMC article.
Systems proteomic analysis reveals that clusterin and tissue inhibitor of metalloproteinases 3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy.
Manousopoulou A, Gatherer M, Smith C, Nicoll JAR, Woelk CH, Johnson M, Kalaria R, Attems J, Garbis SD, Carare RO. Manousopoulou A, et al. Among authors: gatherer m. Neuropathol Appl Neurobiol. 2017 Oct;43(6):492-504. doi: 10.1111/nan.12342. Epub 2016 Oct 5. Neuropathol Appl Neurobiol. 2017. PMID: 27543695 Free PMC article.
Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways.
Wojtas AM, Kang SS, Olley BM, Gatherer M, Shinohara M, Lozano PA, Liu CC, Kurti A, Baker KE, Dickson DW, Yue M, Petrucelli L, Bu G, Carare RO, Fryer JD. Wojtas AM, et al. Among authors: gatherer m. Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6962-E6971. doi: 10.1073/pnas.1701137114. Epub 2017 Jul 12. Proc Natl Acad Sci U S A. 2017. PMID: 28701379 Free PMC article.
20 results