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General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.
Bouazza N, Dokoumetzidis A, Knibbe CAJ, de Wildt SN, Ambery C, De Cock PA, Gasthuys E, Foissac F, Urien S, Hamberg AK, Poggesi I, Zhao W, Vermeulen A, Standing JF, Tréluyer JM; c4c Expert group on Pharmacometrics. Bouazza N, et al. Among authors: gasthuys e. Br J Clin Pharmacol. 2022 Dec;88(12):4985-4996. doi: 10.1111/bcp.15571. Epub 2022 Nov 8. Br J Clin Pharmacol. 2022. PMID: 36256514 Free article. Review.
Altered intravenous drug disposition in people living with cystic fibrosis: A meta-analysis integrating top-down and bottom-up data.
De Sutter PJ, Van Haeverbeke M, Van Braeckel E, Van Biervliet S, Van Bocxlaer J, Vermeulen A, Gasthuys E. De Sutter PJ, et al. Among authors: gasthuys e. CPT Pharmacometrics Syst Pharmacol. 2022 Aug;11(8):951-966. doi: 10.1002/psp4.12832. Epub 2022 Jun 29. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35748042 Free PMC article. Review.
Unravelling the pharmacokinetics of aflatoxin B1: In vitro determination of Michaelis-Menten constants, intrinsic clearance and the metabolic contribution of CYP1A2 and CYP3A4 in pooled human liver microsomes.
Lootens O, De Boevre M, Gasthuys E, Van Bocxlaer J, Vermeulen A, De Saeger S. Lootens O, et al. Among authors: gasthuys e. Front Microbiol. 2022 Aug 29;13:988083. doi: 10.3389/fmicb.2022.988083. eCollection 2022. Front Microbiol. 2022. PMID: 36110298 Free PMC article.
29 results