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Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma.
Sonntag R, Giebeler N, Nevzorova YA, Bangen JM, Fahrenkamp D, Lambertz D, Haas U, Hu W, Gassler N, Cubero FJ, Müller-Newen G, Abdallah AT, Weiskirchen R, Ticconi F, Costa IG, Barbacid M, Trautwein C, Liedtke C. Sonntag R, et al. Among authors: gassler n. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9282-9287. doi: 10.1073/pnas.1807155115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150405 Free PMC article.
Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice.
Hao F, Cubero FJ, Ramadori P, Liao L, Haas U, Lambertz D, Sonntag R, Bangen JM, Gassler N, Hoss M, Streetz KL, Reissing J, Zimmermann HW, Trautwein C, Liedtke C, Nevzorova YA. Hao F, et al. Among authors: gassler n. Cell Death Dis. 2017 Oct 26;8(10):e3152. doi: 10.1038/cddis.2017.532. Cell Death Dis. 2017. PMID: 29072704 Free PMC article.
Targeting Wnt Signaling via Notch in Intestinal Carcinogenesis.
Kaemmerer E, Jeon MK, Berndt A, Liedtke C, Gassler N. Kaemmerer E, et al. Among authors: gassler n. Cancers (Basel). 2019 Apr 18;11(4):555. doi: 10.3390/cancers11040555. Cancers (Basel). 2019. PMID: 31003440 Free PMC article. Review.
CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence.
Mossanen JC, Kohlhepp M, Wehr A, Krenkel O, Liepelt A, Roeth AA, Möckel D, Heymann F, Lammers T, Gassler N, Hermann J, Jankowski J, Neumann UP, Luedde T, Trautwein C, Tacke F. Mossanen JC, et al. Among authors: gassler n. Gastroenterology. 2019 May;156(6):1877-1889.e4. doi: 10.1053/j.gastro.2019.01.247. Epub 2019 Jan 30. Gastroenterology. 2019. PMID: 30710528
209 results