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Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB. Preston S, et al. Among authors: gasser rb. FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7. FASEB J. 2017. PMID: 28687609
Tetrahydroquinoxalines induce a lethal evisceration phenotype in Haemonchus contortus in vitro.
Jiao Y, Preston S, Garcia-Bustos JF, Baell JB, Ventura S, Le T, McNamara N, Nguyen N, Botteon A, Skinner C, Danne J, Ellis S, Koehler AV, Wang T, Chang BCH, Hofmann A, Jabbar A, Gasser RB. Jiao Y, et al. Among authors: gasser rb. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:59-71. doi: 10.1016/j.ijpddr.2018.12.007. Epub 2018 Dec 30. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30690282 Free PMC article.
Selected α-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro.
Herath HMPD, Preston S, Jabbar A, Garcia-Bustos J, Addison RS, Hayes S, Rali T, Wang T, Koehler AV, Chang BCH, Hofmann A, Davis RA, Gasser RB. Herath HMPD, et al. Among authors: gasser rb. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:72-79. doi: 10.1016/j.ijpddr.2018.12.006. Epub 2019 Jan 4. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30739078 Free PMC article.
Identification of Fromiamycalin and Halaminol A from Australian Marine Sponge Extracts with Anthelmintic Activity against Haemonchus contortus.
Herath HMPD, Preston S, Jabbar A, Garcia-Bustos J, Taki AC, Addison RS, Hayes S, Beattie KD, McGee SL, Martin SD, Ekins MG, Hooper JNA, Chang BCH, Hofmann A, Davis RA, Gasser RB. Herath HMPD, et al. Among authors: gasser rb. Mar Drugs. 2019 Oct 23;17(11):598. doi: 10.3390/md17110598. Mar Drugs. 2019. PMID: 31652835 Free PMC article.
Synthesis and structure-activity relationship study of pyrrolidine-oxadiazoles as anthelmintics against Haemonchus contortus.
Ruan B, Zhang Y, Tadesse S, Preston S, Taki AC, Jabbar A, Hofmann A, Jiao Y, Garcia-Bustos J, Harjani J, Le TG, Varghese S, Teguh S, Xie Y, Odiba J, Hu M, Gasser RB, Baell J. Ruan B, et al. Among authors: gasser rb. Eur J Med Chem. 2020 Mar 15;190:112100. doi: 10.1016/j.ejmech.2020.112100. Epub 2020 Jan 25. Eur J Med Chem. 2020. PMID: 32018095
738 results