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Genetic retargeting of E3 ligases to enhance CAR T cell therapy.
Lane IC, Kembuan G, Carreiro J, Kann MC, Lin W, Bouffard AA, Kreuzer J, Morris R, Schneider EM, Kim JY, Zou C, Salas-Benito D, Gasser JA, Leick MB, Słabicki M, Haas W, Maus MV, Jan M. Lane IC, et al. Among authors: gasser ja. Cell Chem Biol. 2024 Feb 15;31(2):338-348.e5. doi: 10.1016/j.chembiol.2023.10.024. Epub 2023 Nov 20. Cell Chem Biol. 2024. PMID: 37989314
The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein.
Zou C, Yoon H, Park PMC, Patten JJ, Pellman J, Carreiro J, Tsai JM, Li YD, Roy Burman SS, Donovan KA, Gasser J, Sperling AS, Nowak RP, Fischer ES, Davey RA, Ebert BL, Słabicki M. Zou C, et al. Among authors: gasser j. iScience. 2023 May 19;26(5):106601. doi: 10.1016/j.isci.2023.106601. Epub 2023 Apr 8. iScience. 2023. PMID: 37095859 Free PMC article.
The circadian transcription factor ARNTL2 is regulated by weight-loss interventions in human white adipose tissue and inhibits adipogenesis.
Mandl M, Viertler HP, Zopoglou M, Mitterberger-Vogt MC, Gasser J, Hatzmann FM, Rauchenwald T, Zwierzina ME, Mattesich M, Weiss AKH, Mottes L, Brucker C, Waldegger P, Pierer G, Zwerschke W. Mandl M, et al. Among authors: gasser j. Cell Death Discov. 2022 Nov 3;8(1):443. doi: 10.1038/s41420-022-01239-3. Cell Death Discov. 2022. PMID: 36329012 Free PMC article.
Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells.
Sellar RS, Sperling AS, Słabicki M, Gasser JA, McConkey ME, Donovan KA, Mageed N, Adams DN, Zou C, Miller PG, Dutta RK, Boettcher S, Lin AE, Sandoval B, Quevedo Barrios VA, Kovalcik V, Koeppel J, Henderson EK, Fink EC, Yang L, Chan A, Pokharel SP, Bergstrom EJ, Burt R, Udeshi ND, Carr SA, Fischer ES, Chen CW, Ebert BL. Sellar RS, et al. Among authors: gasser ja. J Clin Invest. 2022 Aug 15;132(16):e153514. doi: 10.1172/JCI153514. J Clin Invest. 2022. PMID: 35763353 Free PMC article.
194 results