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mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
Garros-Regulez L, Aldaz P, Arrizabalaga O, Moncho-Amor V, Carrasco-Garcia E, Manterola L, Moreno-Cugnon L, Barrena C, Villanua J, Ruiz I, Pollard S, Lovell-Badge R, Sampron N, Garcia I, Matheu A. Garros-Regulez L, et al. Expert Opin Ther Targets. 2016;20(4):393-405. doi: 10.1517/14728222.2016.1151002. Expert Opin Ther Targets. 2016. PMID: 26878385 Free PMC article.
Oncogenic activity of SOX1 in glioblastoma.
Garcia I, Aldaregia J, Marjanovic Vicentic J, Aldaz P, Moreno-Cugnon L, Torres-Bayona S, Carrasco-Garcia E, Garros-Regulez L, Egaña L, Rubio A, Pollard S, Stevanovic M, Sampron N, Matheu A. Garcia I, et al. Among authors: garros regulez l. Sci Rep. 2017 Apr 20;7:46575. doi: 10.1038/srep46575. Sci Rep. 2017. PMID: 28425506 Free PMC article.
Targeting SOX2 as a Therapeutic Strategy in Glioblastoma.
Garros-Regulez L, Garcia I, Carrasco-Garcia E, Lantero A, Aldaz P, Moreno-Cugnon L, Arrizabalaga O, Undabeitia J, Torres-Bayona S, Villanua J, Ruiz I, Egaña L, Sampron N, Matheu A. Garros-Regulez L, et al. Front Oncol. 2016 Oct 24;6:222. doi: 10.3389/fonc.2016.00222. eCollection 2016. Front Oncol. 2016. PMID: 27822457 Free PMC article. Review.
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response.
Arrizabalaga O, Moreno-Cugnon L, Auzmendi-Iriarte J, Aldaz P, Ibanez de Caceres I, Garros-Regulez L, Moncho-Amor V, Torres-Bayona S, Pernía O, Pintado-Berninches L, Carrasco-Ramirez P, Cortes-Sempere M, Rosas R, Sanchez-Gomez P, Ruiz I, Caren H, Pollard S, Garcia I, Sacido AA, Lovell-Badge R, Belda-Iniesta C, Sampron N, Perona R, Matheu A. Arrizabalaga O, et al. Among authors: garros regulez l. Oncogenesis. 2017 Dec 14;6(12):401. doi: 10.1038/s41389-017-0003-9. Oncogenesis. 2017. PMID: 29284798 Free PMC article.
SOX3 can promote the malignant behavior of glioblastoma cells.
Marjanovic Vicentic J, Drakulic D, Garcia I, Vukovic V, Aldaz P, Puskas N, Nikolic I, Tasic G, Raicevic S, Garros-Regulez L, Sampron N, Atkinson MJ, Anastasov N, Matheu A, Stevanovic M. Marjanovic Vicentic J, et al. Among authors: garros regulez l. Cell Oncol (Dordr). 2019 Feb;42(1):41-54. doi: 10.1007/s13402-018-0405-5. Epub 2018 Sep 12. Cell Oncol (Dordr). 2019. PMID: 30209685