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Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12.
Garris CS, Arlauckas SP, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, Pierce RH, Le MH, Algazi AP, Daud AI, Pai SI, Zippelius A, Weissleder R, Pittet MJ. Garris CS, et al. Immunity. 2018 Dec 18;49(6):1148-1161.e7. doi: 10.1016/j.immuni.2018.09.024. Epub 2018 Dec 11. Immunity. 2018. PMID: 30552023 Free PMC article.
Common TLR5 mutations control cancer progression.
Pfirschke C, Garris C, Pittet MJ. Pfirschke C, et al. Cancer Cell. 2015 Jan 12;27(1):1-3. doi: 10.1016/j.ccell.2014.12.008. Cancer Cell. 2015. PMID: 25584886 Free article.
ER Stress in Dendritic Cells Promotes Cancer.
Garris CS, Pittet MJ. Garris CS, et al. Cell. 2015 Jun 18;161(7):1492-3. doi: 10.1016/j.cell.2015.06.006. Cell. 2015. PMID: 26091029 Free article.
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy.
Pfirschke C, Engblom C, Rickelt S, Cortez-Retamozo V, Garris C, Pucci F, Yamazaki T, Poirier-Colame V, Newton A, Redouane Y, Lin YJ, Wojtkiewicz G, Iwamoto Y, Mino-Kenudson M, Huynh TG, Hynes RO, Freeman GJ, Kroemer G, Zitvogel L, Weissleder R, Pittet MJ. Pfirschke C, et al. Immunity. 2016 Feb 16;44(2):343-54. doi: 10.1016/j.immuni.2015.11.024. Epub 2016 Feb 9. Immunity. 2016. PMID: 26872698 Free PMC article.
SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions.
Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, Alvarez D, Sprachman M, Evavold C, Magnuson A, von Andrian UH, Glatz K, Breakefield XO, Mempel TR, Weissleder R, Pittet MJ. Pucci F, et al. Science. 2016 Apr 8;352(6282):242-6. doi: 10.1126/science.aaf1328. Epub 2016 Mar 17. Science. 2016. PMID: 26989197 Free PMC article.
PF4 Promotes Platelet Production and Lung Cancer Growth.
Pucci F, Rickelt S, Newton AP, Garris C, Nunes E, Evavold C, Pfirschke C, Engblom C, Mino-Kenudson M, Hynes RO, Weissleder R, Pittet MJ. Pucci F, et al. Cell Rep. 2016 Nov 8;17(7):1764-1772. doi: 10.1016/j.celrep.2016.10.031. Cell Rep. 2016. PMID: 27829148 Free PMC article.
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils.
Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ. Engblom C, et al. Science. 2017 Dec 1;358(6367):eaal5081. doi: 10.1126/science.aal5081. Science. 2017. PMID: 29191879 Free PMC article.
38 results