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Prototypic long pentraxin PTX3 is present in breast milk, spreads in tissues, and protects neonate mice from Pseudomonas aeruginosa lung infection.
Jaillon S, Mancuso G, Hamon Y, Beauvillain C, Cotici V, Midiri A, Bottazzi B, Nebuloni M, Garlanda C, Frémaux I, Gauchat JF, Descamps P, Beninati C, Mantovani A, Jeannin P, Delneste Y. Jaillon S, et al. Among authors: garlanda c. J Immunol. 2013 Aug 15;191(4):1873-82. doi: 10.4049/jimmunol.1201642. Epub 2013 Jul 17. J Immunol. 2013. PMID: 23863905
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response.
Garlanda C, Hirsch E, Bozza S, Salustri A, De Acetis M, Nota R, Maccagno A, Riva F, Bottazzi B, Peri G, Doni A, Vago L, Botto M, De Santis R, Carminati P, Siracusa G, Altruda F, Vecchi A, Romani L, Mantovani A. Garlanda C, et al. Nature. 2002 Nov 14;420(6912):182-6. doi: 10.1038/nature01195. Nature. 2002. PMID: 12432394
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.
Salustri A, Garlanda C, Hirsch E, De Acetis M, Maccagno A, Bottazzi B, Doni A, Bastone A, Mantovani G, Beck Peccoz P, Salvatori G, Mahoney DJ, Day AJ, Siracusa G, Romani L, Mantovani A. Salustri A, et al. Among authors: garlanda c. Development. 2004 Apr;131(7):1577-86. doi: 10.1242/dev.01056. Epub 2004 Mar 3. Development. 2004. PMID: 14998931 Free article.
252 results