Gardiner SJ - Search Results

1

Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio.

Gardiner SJ, Gearry RB, Burt MJ, Chalmers-Watson T, Chapman BA, Ross AG, Stedman CA, Huelsen A, Barclay ML. Gardiner SJ, et al. J Gastroenterol Hepatol. 2011 Jan;26(1):49-54. doi: 10.1111/j.1440-1746.2010.06489.x. J Gastroenterol Hepatol. 2011. PMID: 21175793

2

Two cases of thiopurine methyltransferase (TPMT) deficiency--a lucky save and a near miss with azathioprine.

Gardiner SJ, Gearry RB, Barclay ML, Begg EJ. Gardiner SJ, et al. Br J Clin Pharmacol. 2006 Oct;62(4):473-6. doi: 10.1111/j.1365-2125.2005.02474.x. Br J Clin Pharmacol. 2006. PMID: 16995868 Free PMC article.

3

Thiopurine dose in intermediate and normal metabolizers of thiopurine methyltransferase may differ three-fold.

Gardiner SJ, Gearry RB, Begg EJ, Zhang M, Barclay ML. Gardiner SJ, et al. Clin Gastroenterol Hepatol. 2008 Jun;6(6):654-60; quiz 604. doi: 10.1016/j.cgh.2008.02.032. Epub 2008 May 7. Clin Gastroenterol Hepatol. 2008. PMID: 18467186 Clinical Trial.

4

Severe hepatotoxicity with high 6-methylmercaptopurine nucleotide concentrations after thiopurine dose escalation due to low 6-thioguanine nucleotides.

Gardiner SJ, Gearry RB, Burt MJ, Ding SL, Barclay ML. Gardiner SJ, et al. Eur J Gastroenterol Hepatol. 2008 Dec;20(12):1238-42. doi: 10.1097/MEG.0b013e3282ffda37. Eur J Gastroenterol Hepatol. 2008. PMID: 18989148

5

Pharmacoeconomic analyses of azathioprine, methotrexate and prospective pharmacogenetic testing for the management of inflammatory bowel disease.

Priest VL, Begg EJ, Gardiner SJ, Frampton CM, Gearry RB, Barclay ML, Clark DW, Hansen P. Priest VL, et al. Among authors: gardiner sj. Pharmacoeconomics. 2006;24(8):767-81. doi: 10.2165/00019053-200624080-00004. Pharmacoeconomics. 2006. PMID: 16898847

6

Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother-infant pairs.

Gardiner SJ, Gearry RB, Roberts RL, Zhang M, Barclay ML, Begg EJ. Gardiner SJ, et al. Br J Clin Pharmacol. 2006 Oct;62(4):453-6. doi: 10.1111/j.1365-2125.2006.02639.x. Br J Clin Pharmacol. 2006. PMID: 16995866 Free PMC article.

7

6-thioguanine nucleotides and thiopurine methyltransferase activity: important factors determining response to treatment and incidence of adverse effects from azathioprine and 6-MP.

Gearry R, Barclay M, Gardiner S, Zhang M. Gearry R, et al. N Z Med J. 2003 Jul 25;116(1178):U531. N Z Med J. 2003. PMID: 12897892 No abstract available.

8

Comment: Breast-feeding during maternal use of azathioprine.

Gardiner SJ, Gearry RB, Roberts RL, Zhang M, Barclay ML, Begg EJ. Gardiner SJ, et al. Ann Pharmacother. 2007 Apr;41(4):719-20; author reply 720. doi: 10.1345/aph.1H152a. Epub 2007 Mar 27. Ann Pharmacother. 2007. PMID: 17389671 No abstract available.

9

Genetic polymorphism and outcomes with azathioprine and 6-mercaptopurine.

Gardiner SJ, Begg EJ, Barclay ML, Kirkpatrick CM. Gardiner SJ, et al. Adverse Drug React Toxicol Rev. 2000 Dec;19(4):293-312. Adverse Drug React Toxicol Rev. 2000. PMID: 11212460 Review. No abstract available.

10

Thiopurine treatment in inflammatory bowel disease.

Gardiner SJ, Begg EJ, Sau A, Marinaki A, Gearry RB, Barclay ML. Gardiner SJ, et al. Clin Pharmacokinet. 2007;46(9):803-4; author reply 805. doi: 10.2165/00003088-200746090-00007. Clin Pharmacokinet. 2007. PMID: 17713977 No abstract available.

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