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Discovery of functional antibodies targeting ion channels.
Wilkinson TC, Gardener MJ, Williams WA. Wilkinson TC, et al. Among authors: gardener mj. J Biomol Screen. 2015 Apr;20(4):454-67. doi: 10.1177/1087057114560698. Epub 2014 Dec 3. J Biomol Screen. 2015. PMID: 25473082 Review.
Anti-PrPC antibody rescues cognition and synapses in transgenic alzheimer mice.
Cox TO, Gunther EC, Brody AH, Chiasseu MT, Stoner A, Smith LM, Haas LT, Hammersley J, Rees G, Dosanjh B, Groves M, Gardener M, Dobson C, Vaughan T, Chessell I, Billinton A, Strittmatter SM. Cox TO, et al. Ann Clin Transl Neurol. 2019 Feb 27;6(3):554-574. doi: 10.1002/acn3.730. eCollection 2019 Mar. Ann Clin Transl Neurol. 2019. PMID: 30911579 Free PMC article.
Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2.
Popovic B, Breed J, Rees DG, Gardener MJ, Vinall LM, Kemp B, Spooner J, Keen J, Minter R, Uddin F, Colice G, Wilkinson T, Vaughan T, May RD. Popovic B, et al. Among authors: gardener mj. J Mol Biol. 2017 Jan 20;429(2):208-219. doi: 10.1016/j.jmb.2016.12.005. Epub 2016 Dec 9. J Mol Biol. 2017. PMID: 27956146 Free article.
Evolution of biologics screening technologies.
Cariuk P, Gardener MJ, Vaughan TJ. Cariuk P, et al. Among authors: gardener mj. Pharmaceuticals (Basel). 2013 May 14;6(5):681-8. doi: 10.3390/ph6050681. Pharmaceuticals (Basel). 2013. PMID: 24276173 Free PMC article.
15 results