Garcia-Perez L - Search Results

1

Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.

Cordes M, Canté-Barrett K, van den Akker EB, Moretti FA, Kiełbasa SM, Vloemans SA, Garcia-Perez L, Teodosio C, van Dongen JJM, Pike-Overzet K, Reinders MJT, Staal FJT. Cordes M, et al. Sci Immunol. 2022 Nov 18;7(77):eade0182. doi: 10.1126/sciimmunol.ade0182. Epub 2022 Nov 11. Sci Immunol. 2022. PMID: 36367948

2

A Novel Branched DNA-Based Flowcytometric Method for Single-Cell Characterization of Gene Therapy Products and Expression of Therapeutic Genes.

Garcia-Perez L, van Eggermond MCJA, Maietta E, van der Hoorn MP, Pike-Overzet K, Staal FJT. Garcia-Perez L, et al. Front Immunol. 2021 Jan 28;11:607991. doi: 10.3389/fimmu.2020.607991. eCollection 2020. Front Immunol. 2021. PMID: 33584681 Free PMC article.

3

Combining Mobilizing Agents with Busulfan to Reduce Chemotherapy-Based Conditioning for Hematopoietic Stem Cell Transplantation.

Garcia-Perez L, van Roon L, Schilham MW, Lankester AC, Pike-Overzet K, Staal FJT. Garcia-Perez L, et al. Cells. 2021 Apr 30;10(5):1077. doi: 10.3390/cells10051077. Cells. 2021. PMID: 33946560 Free PMC article.

4

Axin2/Conductin Is Required for Normal Haematopoiesis and T Lymphopoiesis.

de Roo JJD, Chhatta A, Garcia-Perez L, Naber BAE, Vloemans SA, Salvatori DCF, Pike-Overzet K, Mikkers H, Staal FJT. de Roo JJD, et al. Cells. 2022 Aug 28;11(17):2679. doi: 10.3390/cells11172679. Cells. 2022. PMID: 36078085 Free PMC article.

5

ImSpectR - R package to quantify immune repertoire diversity in spectratype and repertoire sequencing data.

Cordes M, Pike-Overzet K, van Eggermond M, Vloemans S, Baert MR, Garcia-Perez L, Staal FJT, Reinders MJT, van den Akker E. Cordes M, et al. Bioinformatics. 2019 Oct 30;36(6):1930-2. doi: 10.1093/bioinformatics/btz804. Online ahead of print. Bioinformatics. 2019. PMID: 31665245 Free PMC article.

6

Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID.

Garcia-Perez L, van Eggermond M, van Roon L, Vloemans SA, Cordes M, Schambach A, Rothe M, Berghuis D, Lagresle-Peyrou C, Cavazzana M, Zhang F, Thrasher AJ, Salvatori D, Meij P, Villa A, Van Dongen JJM, Zwaginga JJ, van der Burg M, Gaspar HB, Lankester A, Staal FJT, Pike-Overzet K. Garcia-Perez L, et al. Mol Ther Methods Clin Dev. 2020 Mar 31;17:666-682. doi: 10.1016/j.omtm.2020.03.016. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32322605 Free PMC article.

7

Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side.

Garcia-Perez L, Ordas A, Canté-Barrett K, Meij P, Pike-Overzet K, Lankester A, Staal FJT. Garcia-Perez L, et al. Pharmaceutics. 2020 Jun 13;12(6):549. doi: 10.3390/pharmaceutics12060549. Pharmaceutics. 2020. PMID: 32545727 Free PMC article. Review.

8

Aberrant Wnt Signaling in Leukemia.

Staal FJ, Famili F, Garcia Perez L, Pike-Overzet K. Staal FJ, et al. Cancers (Basel). 2016 Aug 26;8(9):78. doi: 10.3390/cancers8090078. Cancers (Basel). 2016. PMID: 27571104 Free PMC article. Review.

9

Functional definition of a transcription factor hierarchy regulating T cell lineage commitment.

Garcia-Perez L, Famili F, Cordes M, Brugman M, van Eggermond M, Wu H, Chouaref J, Granado DSL, Tiemessen MM, Pike-Overzet K, Daxinger L, Staal FJT. Garcia-Perez L, et al. Sci Adv. 2020 Jul 31;6(31):eaaw7313. doi: 10.1126/sciadv.aaw7313. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32789164 Free PMC article.

10

Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia.

Rahman S, Magnussen M, León TE, Farah N, Li Z, Abraham BJ, Alapi KZ, Mitchell RJ, Naughton T, Fielding AK, Pizzey A, Bustraan S, Allen C, Popa T, Pike-Overzet K, Garcia-Perez L, Gale RE, Linch DC, Staal FJT, Young RA, Look AT, Mansour MR. Rahman S, et al. Blood. 2017 Jun 15;129(24):3221-3226. doi: 10.1182/blood-2016-09-742148. Epub 2017 Mar 7. Blood. 2017. PMID: 28270453 Free PMC article.

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