Garcia-Mera X - Search Results

1

A_2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models.

Tay AHM, Prieto-Díaz R, Neo S, Tong L, Chen X, Carannante V, Önfelt B, Hartman J, Haglund F, Majellaro M, Azuaje J, Garcia-Mera X, Brea JM, Loza MI, Jespers W, Gutierrez-de-Teran H, Sotelo E, Lundqvist A. Tay AHM, et al. Among authors: garcia mera x. J Immunother Cancer. 2022 May;10(5):e004592. doi: 10.1136/jitc-2022-004592. J Immunother Cancer. 2022. PMID: 35580926 Free PMC article.

2

1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.

Fernández F, Caamaño O, Isabel Nieto M, López C, García-Mera X, Stefanachi A, Nicolotti O, Isabel Loza M, Brea J, Esteve C, Segarra V, Vidal B, Carotti A. Fernández F, et al. Bioorg Med Chem. 2009 May 15;17(10):3618-29. doi: 10.1016/j.bmc.2009.03.062. Epub 2009 Apr 5. Bioorg Med Chem. 2009. PMID: 19398343

3

Divergent solution-phase synthesis of diarylpyrimidine libraries as selective A3 adenosine receptor antagonists.

Yaziji V, Coelho A, El Maatougui A, Brea J, Loza MI, Garcia-Mera X, Sotelo E. Yaziji V, et al. J Comb Chem. 2009 Jul-Aug;11(4):519-22. doi: 10.1021/cc900044k. J Comb Chem. 2009. PMID: 19472983

4

Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.

Balo MC, Brea J, Caamaño O, Fernández F, García-Mera X, López C, Loza MI, Nieto MI, Rodríguez-Borges JE. Balo MC, et al. Bioorg Med Chem. 2009 Sep 15;17(18):6755-60. doi: 10.1016/j.bmc.2009.07.034. Epub 2009 Jul 23. Bioorg Med Chem. 2009. PMID: 19682912

5

Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.

Rodríguez-Borges JE, García-Mera X, Balo MC, Brea J, Caamaño O, Fernández F, López C, Loza MI, Nieto MI. Rodríguez-Borges JE, et al. Bioorg Med Chem. 2010 Mar 1;18(5):2001-9. doi: 10.1016/j.bmc.2010.01.028. Epub 2010 Jan 15. Bioorg Med Chem. 2010. PMID: 20137957

6

Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists.

Nieto MI, Balo MC, Brea J, Caamaño O, Fernández F, García-Mera X, López C, Loza MI, Rodríguez-Borges JE, Vidal B. Nieto MI, et al. Eur J Med Chem. 2010 Jul;45(7):2884-92. doi: 10.1016/j.ejmech.2010.03.011. Epub 2010 Mar 12. Eur J Med Chem. 2010. PMID: 20371139

7

Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists.

Yaziji V, Rodríguez D, Gutiérrez-de-Terán H, Coelho A, Caamaño O, García-Mera X, Brea J, Loza MI, Cadavid MI, Sotelo E. Yaziji V, et al. J Med Chem. 2011 Jan 27;54(2):457-71. doi: 10.1021/jm100843z. Epub 2010 Dec 27. J Med Chem. 2011. PMID: 21186795

8

Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold.

Yaziji V, Rodríguez D, Coelho A, García-Mera X, El Maatougui A, Brea J, Loza MI, Cadavid MI, Gutiérrez-de-Terán H, Sotelo E. Yaziji V, et al. Eur J Med Chem. 2013 Jan;59:235-42. doi: 10.1016/j.ejmech.2012.11.010. Epub 2012 Nov 24. Eur J Med Chem. 2013. PMID: 23231967

9

Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of L-prolyl-L-leucyl-glycinamide (PLG) modified in the L-proline or L-proline and L-leucine scaffolds.

Ferreira da Costa J, Caamaño O, Fernández F, García-Mera X, Sampaio-Dias IE, Brea JM, Cadavid MI. Ferreira da Costa J, et al. Eur J Med Chem. 2013 Nov;69:146-58. doi: 10.1016/j.ejmech.2013.08.001. Epub 2013 Aug 22. Eur J Med Chem. 2013. PMID: 24013414

10

Ugi-based approaches to quinoxaline libraries.

Azuaje J, El Maatougui A, García-Mera X, Sotelo E. Azuaje J, et al. ACS Comb Sci. 2014 Aug 11;16(8):403-11. doi: 10.1021/co500036n. Epub 2014 May 14. ACS Comb Sci. 2014. PMID: 24800648

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