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A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary.
Skanji R, Andrieux K, Lalanne M, Caron J, Bourgaux C, Degrouard J, Brisset F, Gueutin C, Chacun H, Dereuddre-Bosquet N, Paci A, Vassal G, Bauduin L, Garcia-Argote S, Rousseau B, Clayette P, Desmaële D, Couvreur P. Skanji R, et al. Int J Pharm. 2011 Jul 29;414(1-2):285-97. doi: 10.1016/j.ijpharm.2011.05.005. Epub 2011 May 10. Int J Pharm. 2011. PMID: 21596125
Pharmacokinetics, biodistribution and metabolism of squalenoyl adenosine nanoparticles in mice using dual radio-labeling and radio-HPLC analysis.
Gaudin A, Lepetre-Mouelhi S, Mougin J, Parrod M, Pieters G, Garcia-Argote S, Loreau O, Goncalves J, Chacun H, Courbebaisse Y, Clayette P, Desmaële D, Rousseau B, Andrieux K, Couvreur P. Gaudin A, et al. J Control Release. 2015 Aug 28;212:50-8. doi: 10.1016/j.jconrel.2015.06.016. Epub 2015 Jun 16. J Control Release. 2015. PMID: 26087468 Free PMC article.
Multiple Site Hydrogen Isotope Labelling of Pharmaceuticals.
Daniel-Bertrand M, Garcia-Argote S, Palazzolo A, Mustieles Marin I, Fazzini PF, Tricard S, Chaudret B, Derdau V, Feuillastre S, Pieters G. Daniel-Bertrand M, et al. Among authors: garcia argote s. Angew Chem Int Ed Engl. 2020 Nov 16;59(47):21114-21120. doi: 10.1002/anie.202008519. Epub 2020 Sep 15. Angew Chem Int Ed Engl. 2020. PMID: 33463019
A Polymer Prodrug Strategy to Switch from Intravenous to Subcutaneous Cancer Therapy for Irritant/Vesicant Drugs.
Bordat A, Boissenot T, Ibrahim N, Ferrere M, Levêque M, Potiron L, Denis S, Garcia-Argote S, Carvalho O, Abadie J, Cailleau C, Pieters G, Tsapis N, Nicolas J. Bordat A, et al. Among authors: garcia argote s. J Am Chem Soc. 2022 Oct 19;144(41):18844-18860. doi: 10.1021/jacs.2c04944. Epub 2022 Oct 4. J Am Chem Soc. 2022. PMID: 36193551 Free PMC article.
Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury.
Gaudin A, Yemisci M, Eroglu H, Lepetre-Mouelhi S, Turkoglu OF, Dönmez-Demir B, Caban S, Sargon MF, Garcia-Argote S, Pieters G, Loreau O, Rousseau B, Tagit O, Hildebrandt N, Le Dantec Y, Mougin J, Valetti S, Chacun H, Nicolas V, Desmaële D, Andrieux K, Capan Y, Dalkara T, Couvreur P. Gaudin A, et al. Nat Nanotechnol. 2014;9(12):1054-1062. doi: 10.1038/nnano.2014.274. Epub 2014 Nov 24. Nat Nanotechnol. 2014. PMID: 25420034 Free PMC article.
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