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Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.
Akbari P, Gilani A, Sosina O, Kosmicki JA, Khrimian L, Fang YY, Persaud T, Garcia V, Sun D, Li A, Mbatchou J, Locke AE, Benner C, Verweij N, Lin N, Hossain S, Agostinucci K, Pascale JV, Dirice E, Dunn M; Regeneron Genetics Center; DiscovEHR Collaboration; Kraus WE, Shah SH, Chen YI, Rotter JI, Rader DJ, Melander O, Still CD, Mirshahi T, Carey DJ, Berumen-Campos J, Kuri-Morales P, Alegre-Díaz J, Torres JM, Emberson JR, Collins R, Balasubramanian S, Hawes A, Jones M, Zambrowicz B, Murphy AJ, Paulding C, Coppola G, Overton JD, Reid JG, Shuldiner AR, Cantor M, Kang HM, Abecasis GR, Karalis K, Economides AN, Marchini J, Yancopoulos GD, Sleeman MW, Altarejos J, Della Gatta G, Tapia-Conyer R, Schwartzman ML, Baras A, Ferreira MAR, Lotta LA. Akbari P, et al. Among authors: garcia v. Science. 2021 Jul 2;373(6550):eabf8683. doi: 10.1126/science.abf8683. Science. 2021. PMID: 34210852 Free PMC article.
Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction.
Cheng J, Garcia V, Ding Y, Wu CC, Thakar K, Falck JR, Ramu E, Schwartzman ML. Cheng J, et al. Among authors: garcia v. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1917-24. doi: 10.1161/ATVBAHA.112.248344. Epub 2012 Jun 21. Arterioscler Thromb Vasc Biol. 2012. PMID: 22723444 Free PMC article.
20-HETE and blood pressure regulation: clinical implications.
Wu CC, Gupta T, Garcia V, Ding Y, Schwartzman ML. Wu CC, et al. Among authors: garcia v. Cardiol Rev. 2014 Jan-Feb;22(1):1-12. doi: 10.1097/CRD.0b013e3182961659. Cardiol Rev. 2014. PMID: 23584425 Free PMC article. Review.
Vascular actions of 20-HETE.
Hoopes SL, Garcia V, Edin ML, Schwartzman ML, Zeldin DC. Hoopes SL, et al. Among authors: garcia v. Prostaglandins Other Lipid Mediat. 2015 Jul;120:9-16. doi: 10.1016/j.prostaglandins.2015.03.002. Epub 2015 Mar 23. Prostaglandins Other Lipid Mediat. 2015. PMID: 25813407 Free PMC article. Review.
High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.
Gilani A, Pandey V, Garcia V, Agostinucci K, Singh SP, Schragenheim J, Bellner L, Falck JR, Paudyal MP, Capdevila JH, Abraham NG, Laniado Schwartzman M. Gilani A, et al. Among authors: garcia v. Am J Physiol Regul Integr Comp Physiol. 2018 Nov 1;315(5):R934-R944. doi: 10.1152/ajpregu.00125.2018. Epub 2018 Aug 8. Am J Physiol Regul Integr Comp Physiol. 2018. PMID: 30088983 Free PMC article.
1,644 results