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High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.
Gilani A, Pandey V, Garcia V, Agostinucci K, Singh SP, Schragenheim J, Bellner L, Falck JR, Paudyal MP, Capdevila JH, Abraham NG, Laniado Schwartzman M. Gilani A, et al. Among authors: garcia v. Am J Physiol Regul Integr Comp Physiol. 2018 Nov 1;315(5):R934-R944. doi: 10.1152/ajpregu.00125.2018. Epub 2018 Aug 8. Am J Physiol Regul Integr Comp Physiol. 2018. PMID: 30088983 Free PMC article.
Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction.
Cheng J, Garcia V, Ding Y, Wu CC, Thakar K, Falck JR, Ramu E, Schwartzman ML. Cheng J, et al. Among authors: garcia v. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1917-24. doi: 10.1161/ATVBAHA.112.248344. Epub 2012 Jun 21. Arterioscler Thromb Vasc Biol. 2012. PMID: 22723444 Free PMC article.
Vascular characterization of mice with endothelial expression of cytochrome P450 4F2.
Cheng J, Edin ML, Hoopes SL, Li H, Bradbury JA, Graves JP, DeGraff LM, Lih FB, Garcia V, Shaik JS, Tomer KB, Flake GP, Falck JR, Lee CR, Poloyac SM, Schwartzman ML, Zeldin DC. Cheng J, et al. Among authors: garcia v. FASEB J. 2014 Jul;28(7):2915-31. doi: 10.1096/fj.13-241927. Epub 2014 Mar 25. FASEB J. 2014. PMID: 24668751 Free PMC article.
., Bradbury, J. A., Graves, J. P., DeGraff, L. M., Lih, F. B., Garcia, V., Shaik, J. S. B., Tomer, K. B., Flake, G. P., Falck, J. ...
., Bradbury, J. A., Graves, J. P., DeGraff, L. M., Lih, F. B., Garcia, V., Shaik, J. S. B., Tomer, K. B., Flake, G. P., Falck, …
Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A. Gangadhariah MH, et al. Among authors: garcia v. J Am Soc Nephrol. 2015 Mar;26(3):597-610. doi: 10.1681/ASN.2013090980. Epub 2014 Jul 28. J Am Soc Nephrol. 2015. PMID: 25071086 Free PMC article.
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.
Garcia V, Joseph G, Shkolnik B, Ding Y, Zhang FF, Gotlinger K, Falck JR, Dakarapu R, Capdevila JH, Bernstein KE, Schwartzman ML. Garcia V, et al. Am J Physiol Regul Integr Comp Physiol. 2015 Jul 1;309(1):R71-8. doi: 10.1152/ajpregu.00039.2015. Epub 2015 Apr 29. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 25924878 Free PMC article.
Androgen-sensitive hypertension associated with soluble guanylate cyclase-α1 deficiency is mediated by 20-HETE.
Dordea AC, Vandenwijngaert S, Garcia V, Tainsh RE, Nathan DI, Allen K, Raher MJ, Tainsh LT, Zhang F, Lieb WS, Mikelman S, Kirby A, Stevens C, Thoonen R, Hindle AG, Sips PY, Falck JR, Daly MJ, Brouckaert P, Bloch KD, Bloch DB, Malhotra R, Schwartzman ML, Buys ES. Dordea AC, et al. Among authors: garcia v. Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1790-800. doi: 10.1152/ajpheart.00877.2015. Epub 2016 May 3. Am J Physiol Heart Circ Physiol. 2016. PMID: 27199131 Free PMC article.
1,646 results