Garcia KC - Search Results

1

Facile discovery of surrogate cytokine agonists.

Yen M, Ren J, Liu Q, Glassman CR, Sheahan TP, Picton LK, Moreira FR, Rustagi A, Jude KM, Zhao X, Blish CA, Baric RS, Su LL, Garcia KC. Yen M, et al. Among authors: garcia kc. Cell. 2022 Apr 14;185(8):1414-1430.e19. doi: 10.1016/j.cell.2022.02.025. Epub 2022 Mar 23. Cell. 2022. PMID: 35325595 Free PMC article.

2

How the T cell receptor sees antigen--a structural view.

Garcia KC, Adams EJ. Garcia KC, et al. Cell. 2005 Aug 12;122(3):333-6. doi: 10.1016/j.cell.2005.07.015. Cell. 2005. PMID: 16096054 Free article. Review.

3

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC. LaPorte SL, et al. Among authors: garcia kc. Cell. 2008 Jan 25;132(2):259-72. doi: 10.1016/j.cell.2007.12.030. Cell. 2008. PMID: 18243101 Free PMC article.

4

Structural biology of shared cytokine receptors.

Wang X, Lupardus P, Laporte SL, Garcia KC. Wang X, et al. Among authors: garcia kc. Annu Rev Immunol. 2009;27:29-60. doi: 10.1146/annurev.immunol.24.021605.090616. Annu Rev Immunol. 2009. PMID: 18817510 Free PMC article. Review.

5

Structural linkage between ligand discrimination and receptor activation by type I interferons.

Thomas C, Moraga I, Levin D, Krutzik PO, Podoplelova Y, Trejo A, Lee C, Yarden G, Vleck SE, Glenn JS, Nolan GP, Piehler J, Schreiber G, Garcia KC. Thomas C, et al. Among authors: garcia kc. Cell. 2011 Aug 19;146(4):621-32. doi: 10.1016/j.cell.2011.06.048. Cell. 2011. PMID: 21854986 Free PMC article.

6

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.

Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC. Levin AM, et al. Among authors: garcia kc. Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975. Nature. 2012. PMID: 22446627 Free PMC article.

7

Structural biology. Structural basis for Notch1 engagement of Delta-like 4.

Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. Luca VC, et al. Among authors: garcia kc. Science. 2015 Feb 20;347(6224):847-53. doi: 10.1126/science.1261093. Science. 2015. PMID: 25700513 Free PMC article.

8

Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.

Moraga I, Wernig G, Wilmes S, Gryshkova V, Richter CP, Hong WJ, Sinha R, Guo F, Fabionar H, Wehrman TS, Krutzik P, Demharter S, Plo I, Weissman IL, Minary P, Majeti R, Constantinescu SN, Piehler J, Garcia KC. Moraga I, et al. Among authors: garcia kc. Cell. 2015 Mar 12;160(6):1196-208. doi: 10.1016/j.cell.2015.02.011. Epub 2015 Feb 26. Cell. 2015. PMID: 25728669 Free PMC article.

9

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.

Burg JS, Ingram JR, Venkatakrishnan AJ, Jude KM, Dukkipati A, Feinberg EN, Angelini A, Waghray D, Dror RO, Ploegh HL, Garcia KC. Burg JS, et al. Among authors: garcia kc. Science. 2015 Mar 6;347(6226):1113-7. doi: 10.1126/science.aaa5026. Science. 2015. PMID: 25745166 Free PMC article.

10

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

Spangler JB, Tomala J, Luca VC, Jude KM, Dong S, Ring AM, Votavova P, Pepper M, Kovar M, Garcia KC. Spangler JB, et al. Among authors: garcia kc. Immunity. 2015 May 19;42(5):815-25. doi: 10.1016/j.immuni.2015.04.015. Immunity. 2015. PMID: 25992858 Free PMC article.

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