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TRPC6, a therapeutic target for pulmonary hypertension.
Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Jain PP, et al. Among authors: garcia jgn. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321(6):L1161-L1182. doi: 10.1152/ajplung.00159.2021. Epub 2021 Oct 27. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34704831 Free PMC article.
The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension.
Chen J, Tang H, Sysol JR, Moreno-Vinasco L, Shioura KM, Chen T, Gorshkova I, Wang L, Huang LS, Usatyuk PV, Sammani S, Zhou G, Raj JU, Garcia JG, Berdyshev E, Yuan JX, Natarajan V, Machado RF. Chen J, et al. Am J Respir Crit Care Med. 2014 Nov 1;190(9):1032-43. doi: 10.1164/rccm.201401-0121OC. Am J Respir Crit Care Med. 2014. PMID: 25180446 Free PMC article.
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, Yuan JX. Tang H, et al. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L208-20. doi: 10.1152/ajplung.00242.2014. Epub 2014 Nov 21. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25416384 Free PMC article.
Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells.
Sun X, Kellner M, Desai AA, Wang T, Lu Q, Kangath A, Qu N, Klinger C, Fratz S, Yuan JX, Jacobson JR, Garcia JG, Rafikov R, Fineman JR, Black SM. Sun X, et al. Am J Respir Cell Mol Biol. 2016 Aug;55(2):275-87. doi: 10.1165/rcmb.2015-0185OC. Am J Respir Cell Mol Biol. 2016. PMID: 26959555 Free PMC article.
Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.
Tang H, Yamamura A, Yamamura H, Song S, Fraidenburg DR, Chen J, Gu Y, Pohl NM, Zhou T, Jiménez-Pérez L, Ayon RJ, Desai AA, Goltzman D, Rischard F, Khalpey Z, Black SM, Garcia JG, Makino A, Yuan JX. Tang H, et al. Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L846-59. doi: 10.1152/ajplung.00050.2016. Epub 2016 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26968768 Free PMC article.
466 results