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pH-Responsive Pharmacological Chaperones for Rescuing Mutant Glycosidases.
Mena-Barragán T, Narita A, Matias D, Tiscornia G, Nanba E, Ohno K, Suzuki Y, Higaki K, Garcia Fernández JM, Ortiz Mellet C. Mena-Barragán T, et al. Among authors: garcia fernandez jm. Angew Chem Int Ed Engl. 2015 Sep 28;54(40):11696-700. doi: 10.1002/anie.201505147. Epub 2015 Aug 7. Angew Chem Int Ed Engl. 2015. PMID: 26386364
Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds.
Tiscornia G, Vivas EL, Matalonga L, Berniakovich I, Barragán Monasterio M, Eguizábal C, Gort L, González F, Ortiz Mellet C, García Fernández JM, Ribes A, Veiga A, Izpisua Belmonte JC. Tiscornia G, et al. Among authors: garcia fernandez jm. Hum Mol Genet. 2013 Feb 15;22(4):633-45. doi: 10.1093/hmg/dds471. Epub 2012 Oct 31. Hum Mol Genet. 2013. PMID: 23118351
Trehalose- and glucose-derived glycoamphiphiles: small-molecule and nanoparticle Toll-like receptor 4 (TLR4) modulators.
Rodriguez Lavado J, Sestito SE, Cighetti R, Aguilar Moncayo EM, Oblak A, Lainšček D, Jiménez Blanco JL, García Fernández JM, Ortiz Mellet C, Jerala R, Calabrese V, Peri F. Rodriguez Lavado J, et al. Among authors: garcia fernandez jm. J Med Chem. 2014 Nov 13;57(21):9105-23. doi: 10.1021/jm501182w. Epub 2014 Oct 21. J Med Chem. 2014. PMID: 25268544
Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts.
Mena-Barragán T, García-Moreno MI, Nanba E, Higaki K, Concia AL, Clapés P, García Fernández JM, Ortiz Mellet C. Mena-Barragán T, et al. Among authors: garcia moreno mi, garcia fernandez jm. Eur J Med Chem. 2016 Oct 4;121:880-891. doi: 10.1016/j.ejmech.2015.08.038. Epub 2015 Aug 31. Eur J Med Chem. 2016. PMID: 26361824
Fluorinated Chaperone-β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease.
García-Moreno MI, de la Mata M, Sánchez-Fernández EM, Benito JM, Díaz-Quintana A, Fustero S, Nanba E, Higaki K, Sánchez-Alcázar JA, García Fernández JM, Ortiz Mellet C. García-Moreno MI, et al. Among authors: garcia fernandez jm. J Med Chem. 2017 Mar 9;60(5):1829-1842. doi: 10.1021/acs.jmedchem.6b01550. Epub 2017 Feb 22. J Med Chem. 2017. PMID: 28171725
Plasmid-Templated Control of DNA-Cyclodextrin Nanoparticle Morphology through Molecular Vector Design for Effective Gene Delivery.
Gallego-Yerga L, Benito JM, Blanco-Fernández L, Martínez-Negro M, Vélaz I, Aicart E, Junquera E, Ortiz Mellet C, Tros de Ilarduya C, García Fernández JM. Gallego-Yerga L, et al. Among authors: garcia fernandez jm. Chemistry. 2018 Mar 12;24(15):3825-3835. doi: 10.1002/chem.201705723. Epub 2018 Feb 19. Chemistry. 2018. PMID: 29341305
305 results