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SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.
Kee J, Thudium S, Renner DM, Glastad K, Palozola K, Zhang Z, Li Y, Lan Y, Cesare J, Poleshko A, Kiseleva AA, Truitt R, Cardenas-Diaz FL, Zhang X, Xie X, Kotton DN, Alysandratos KD, Epstein JA, Shi PY, Yang W, Morrisey E, Garcia BA, Berger SL, Weiss SR, Korb E. Kee J, et al. Among authors: garcia ba. Nature. 2022 Oct;610(7931):381-388. doi: 10.1038/s41586-022-05282-z. Epub 2022 Oct 5. Nature. 2022. PMID: 36198800 Free PMC article.
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, Utz PJ, Shi X, Prinjha RK, Lee K, Garcia BA, Bedford MT, Tarakhovsky A, Cheng X, Gozani O. Levy D, et al. Among authors: garcia ba. Nat Immunol. 2011 Jan;12(1):29-36. doi: 10.1038/ni.1968. Epub 2010 Dec 5. Nat Immunol. 2011. PMID: 21131967 Free PMC article.
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.
Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF. Barber MF, et al. Among authors: garcia ba. Nature. 2012 Jul 5;487(7405):114-8. doi: 10.1038/nature11043. Nature. 2012. PMID: 22722849 Free PMC article.
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, Gozani O. Mazur PK, et al. Among authors: garcia ba. Nature. 2014 Jun 12;510(7504):283-7. doi: 10.1038/nature13320. Epub 2014 May 21. Nature. 2014. PMID: 24847881 Free PMC article.
Characterization of BRD4 during mammalian postmeiotic sperm development.
Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL. Bryant JM, et al. Among authors: garcia ba. Mol Cell Biol. 2015 Apr;35(8):1433-48. doi: 10.1128/MCB.01328-14. Epub 2015 Feb 17. Mol Cell Biol. 2015. PMID: 25691659 Free PMC article.
513 results